Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen.
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An induced rebinding model of antigen discriminationDiversity and recognition efficiency of T cell responses to cancerRegulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasmLinking form to function: Biophysical aspects of artificial antigen presenting cell designTCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeysStructural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex ComplexesRelating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccinesStreptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking.TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection.TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.Contribution of T cell receptor affinity to overall avidity for virus-specific CD8+ T cell responsesComplete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigenNanoscale artificial antigen presenting cells for T cell immunotherapyAssessing CD8 T cell number and dysfunction in the presence of antigenT-cell activation by soluble MHC oligomers can be described by a two-parameter binding model.Presentation of antagonist peptides to naive CD4+ T cells abrogates spatial reorganization of class II MHC peptide complexes on the surface of dendritic cells.Development and use of multimeric major histocompatibility complex molecules.Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.Nanoscale ligand spacing influences receptor triggering in T cells and NK cellsInteraction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRsTCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.Quantum dot fluorescence characterizes the nanoscale organization of T cell receptors for antigen.Functional avidity directs T-cell fate in autoreactive CD4+ T cells.Elevated tumor-associated antigen expression suppresses variant peptide vaccine responses.TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines.Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activationT cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation stateAltered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer.Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes.CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection.Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells.The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggeringModulation of MHC binding by lateral association of TCR and coreceptor.Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response.IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites.Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA virusesSignal transduction via the T cell antigen receptor in naïve and effector/memory T cells.Augmenting antitumor T-cell responses to mimotope vaccination by boosting with native tumor antigens.T-cell avidity and tuning: the flexible connection between tolerance and autoimmunity.
P2860
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P2860
Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Increased TCR avidity after T ...... r sensing low-density antigen.
@ast
Increased TCR avidity after T ...... r sensing low-density antigen.
@en
type
label
Increased TCR avidity after T ...... r sensing low-density antigen.
@ast
Increased TCR avidity after T ...... r sensing low-density antigen.
@en
prefLabel
Increased TCR avidity after T ...... r sensing low-density antigen.
@ast
Increased TCR avidity after T ...... r sensing low-density antigen.
@en
P2093
P1433
P1476
Increased TCR avidity after T ...... r sensing low-density antigen.
@en
P2093
P304
P356
10.1016/S1074-7613(09)00099-5
P407
P577
2001-02-01T00:00:00Z