The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition
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The Muscular Dystrophy Gene TMEM5 Encodes a Ribitol β1,4-Xylosyltransferase Required for the Functional Glycosylation of Dystroglycan.Mammalian O-mannosylation of cadherins and plexins is independent of protein O-mannosyltransferases 1 and 2.LARGE2-dependent glycosylation confers laminin-binding ability on proteoglycans.Structure of protein O-mannose kinase reveals a unique active site architecture.Biological roles of glycans.Lassa Virus Cell Entry Reveals New Aspects of Virus-Host Cell InteractionWhat is new in CDG?Recent advancements in understanding mammalian O-mannosylation.Differentiation-related glycan epitopes identify discrete domains of the muscle glycocalyx.3D structural analysis of protein O-mannosyl kinase, POMK, a causative gene product of dystroglycanopathy.Direct Mapping of Additional Modifications on Phosphorylated O-glycans of α-Dystroglycan by Mass Spectrometry Analysis in Conjunction with Knocking Out of Causative Genes for Dystroglycanopathy.Biological Studies and Target Engagement of the 2-C-Methyl-d-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1R,3S)-MMV008138 and Analogs.Protein O-Linked Mannose β-1,4-N-Acetylglucosaminyl-transferase 2 (POMGNT2) Is a Gatekeeper Enzyme for Functional Glycosylation of α-Dystroglycan.Muscular Dystrophy with Ribitol-Phosphate Deficiency: A Novel Post-Translational Mechanism in Dystroglycanopathy.Expression system for structural and functional studies of human glycosylation enzymes.Axl can serve as entry factor for Lassa virus depending on the functional glycosylation of dystroglycan.Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins.Autologous intramuscular transplantation of engineered satellite cells induces exosome-mediated systemic expression of Fukutin-related protein and rescues disease phenotype in a murine model of limb-girdle muscular dystrophy type 2I.Expression in retinal neurons of fukutin and FKRP, the protein products of two dystroglycanopathy-causative genes.Rapid screening of sugar-nucleotide donor specificities of putative glycosyltransferases.TRAPPC11 and GOSR2 mutations associate with hypoglycosylation of α-dystroglycan and muscular dystrophy.Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice
P2860
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P2860
The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition
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2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
The functional O-mannose glyca ...... rimed for matriglycan addition
@ast
The functional O-mannose glyca ...... rimed for matriglycan addition
@en
type
label
The functional O-mannose glyca ...... rimed for matriglycan addition
@ast
The functional O-mannose glyca ...... rimed for matriglycan addition
@en
prefLabel
The functional O-mannose glyca ...... rimed for matriglycan addition
@ast
The functional O-mannose glyca ...... rimed for matriglycan addition
@en
P2093
P2860
P50
P921
P356
P1433
P1476
The functional O-mannose glyca ...... rimed for matriglycan addition
@en
P2093
David Chitayat
Derek L Stemple
Jeremy L Praissman
Kelley W Moremen
Pradeep Kumar Prabhakar
Stanley F Nelson
Stephanie H Stalnaker
P2860
P356
10.7554/ELIFE.14473
P407
P577
2016-04-29T00:00:00Z