By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro.
about
Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus developmentA large semi-synthetic single-chain Fv phage display library based on chicken immunoglobulin genesOligonucleotide-assisted cleavage and ligation: a novel directional DNA cloning technology to capture cDNAs. Application in the construction of a human immune antibody phage-display libraryDiscovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F GlycoproteinConstruction and characterization of single-chain variable fragment antibody library derived from germline rearranged immunoglobulin variable genesPhage display of peptide / major histocompatibility class I complexes.Mapping the epitope in cadherin-like receptors involved in Bacillus thuringiensis Cry1A toxin interaction using phage display.A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies.Human recombinant single-chain antibody fragments, specific for the hypervariable region 1 of hepatitis C virus, from immune phage-display libraries.Neutralizing human anti crotoxin scFv isolated from a nonimmunized phage library.Molecular characterization and applications of recombinant scFv antibodies to CD152 co-stimulatory molecule.By-passing selection: direct screening for antibody-antigen interactions using protein arraysDe novo production of diverse intracellular antibody libraries.Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries.The use of phage display in the study of receptors and their ligands.Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3.Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel.Phage antibodies obtained by competitive selection on complement-resistant Moraxella (Branhamella) catarrhalis recognize the high-molecular-weight outer membrane protein.Human IgG Fc-binding phage antibodies constructed from synovial fluid CD38+ B cells of patients with rheumatoid arthritis show the imprints of an antigen-dependent process of somatic hypermutation and clonal selection.Functional analysis of the CXXC motif using phage antibodies that cross-react with protein disulphide-isomerase family proteins.Production of a human single-chain variable fragment antibody against esophageal carcinomaRibosome display: next-generation display technologies for production of antibodies in vitro.Engineering of monoclonal antibodies and antibody-based fusion proteins: successes and challenges.Synthetic antibodies as therapeutics.Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicityDesign of synthetic antibody libraries.Multiple-antigen immunization of chickens facilitates the generation of recombinant antibodies to autoantigens.Libraries against libraries for combinatorial selection of replicating antigen-antibody pairsDetecting morphologically distinct oligomeric forms of alpha-synuclein.Neutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library.An improved phage-display panning method to produce an HM-1 killer toxin anti-idiotypic antibody.Mining human antibody repertoires.Expression, engineering and characterization of the tumor-targeting heterodimeric immunocytokine F8-IL12.Applications of recombinant antibodies in plant pathology.A novel synthetic naïve human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin.Molecular considerations for development of phage antibody libraries.Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries.Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene librariesIsolation of high affinity human antibodies directly from large synthetic repertoires.Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining.
P2860
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P2860
By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro.
description
1992 nî lūn-bûn
@nan
1992 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
By-passing immunisation. Human ...... segments rearranged in vitro.
@ast
By-passing immunisation. Human ...... segments rearranged in vitro.
@en
type
label
By-passing immunisation. Human ...... segments rearranged in vitro.
@ast
By-passing immunisation. Human ...... segments rearranged in vitro.
@en
prefLabel
By-passing immunisation. Human ...... segments rearranged in vitro.
@ast
By-passing immunisation. Human ...... segments rearranged in vitro.
@en
P1476
By-passing immunisation. Human ...... segments rearranged in vitro.
@en
P2093
Hoogenboom HR
P304
P356
10.1016/0022-2836(92)90894-P
P407
P577
1992-09-01T00:00:00Z