Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status.

Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status.

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http://www.wikidata.org/entity/Q33223047
Dual roles of extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cellsBetulinic acid in complex with a gamma-cyclodextrin derivative decreases proliferation and in vivo tumor development of non-metastatic and metastatic B164A5 cells.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.Inhibition of Ras for cancer treatment: the search continues.Experimental anti-tumor therapy in 3-D: spheroids--old hat or new challenge?Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.Plant-derived triterpenoids and analogues as antitumor and anti-HIV agentsPreclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models.ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence.C2-ceramide induces cell death and protective autophagy in head and neck squamous cell carcinoma cells.Emerging MEK inhibitors.Signaling pathways as therapeutic targets in biliary tract cancer.JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells.Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression.Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells
P2860

Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status.

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http://www.wikidata.org/entity/Q33223047
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
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2006年論文
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2006年論文
@zh-tw
2006年论文
@wuu
name
Signalling responses linked to ...... ma irrespective of p53 status.
@ast
Signalling responses linked to ...... ma irrespective of p53 status.
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type
label
Signalling responses linked to ...... ma irrespective of p53 status.
@ast
Signalling responses linked to ...... ma irrespective of p53 status.
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prefLabel
Signalling responses linked to ...... ma irrespective of p53 status.
@ast
Signalling responses linked to ...... ma irrespective of p53 status.
@en
P1433
P1476
P2093
P2860
P304
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P478
P577
P5875
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P1433
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Signalling responses linked to ...... ma irrespective of p53 status.
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P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698