Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest - sprookjes - yvandenbroek - TriplyDB

Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest

Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest

http://www.wikidata.org/entity/Q33241207

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Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy Cancer prevention with promising natural products: mechanisms of action and molecular targets The novel Akt inhibitor Palomid 529 (P529) enhances the effect of radiotherapy in prostate cancer Growth inhibition and apoptosis induced by osthole, a natural coumarin, in hepatocellular carcinoma Phytoestrogens and risk of prostate cancer: an updated meta-analysis of epidemiologic studies.Cancer biomarker discovery: the entropic hallmark.Progression of renal cell carcinoma is inhibited by genistein and radiation in an orthotopic model.Isoflavones are safe compounds for therapeutical applications - evaluation of in vitro data.Functional foods and their role in cancer prevention and health promotion: a comprehensive review.Effects of genistein supplementation on genome‑wide DNA methylation and gene expression in patients with localized prostate cancer Recent progress on nutraceutical research in prostate cancer.Radiosensitization of prostate cancer by priming the wild-type p53-dependent cellular senescence pathway.Irreversible EGFR inhibitor EKB-569 targets low-LET γ-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma.The p21-dependent radiosensitization of human breast cancer cells by MLN4924, an investigational inhibitor of NEDD8 activating enzyme.Positive outcomes of oil palm phenolics on degenerative diseases in animal models Dietary soy and tea mitigate chronic inflammation and prostate cancer via NFκB pathway in the Noble rat model Genistein suppresses LPS-induced inflammatory response through inhibiting NF-κB following AMP kinase activation in RAW 264.7 macrophages.Apoptosis by dietary agents for prevention and treatment of prostate cancer Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice.Monitoring sunitinib-induced vascular effects to optimize radiotherapy combined with soy isoflavones in murine xenograft tumor Phenylpropanoids in radioregulation: double edged sword.Role of nuclear factor κB-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents.Role of miR-100 in the radioresistance of colorectal cancer cells.Soy isoflavones radiosensitize lung cancer while mitigating normal tissue injury Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR.Chemoprevention in gastrointestinal physiology and disease. Targeting the progression of cancer with natural products: a focus on gastrointestinal cancer.Radiation, inflammation, and immune responses in cancer Mangiferin activates Nrf2-antioxidant response element signaling without reducing the sensitivity to etoposide of human myeloid leukemia cells in vitro.Comparison of the effects of melatonin and genistein on radiation-induced nephrotoxicity: Results of an experimental study.Molecular basis of 'hypoxic' breast cancer cell radio-sensitization: phytochemicals converge on radiation induced Rel signaling.Targeting multiple signal pathways by chemopreventive agents for cancer prevention and therapy.Genistein protects against biomarkers of delayed lung sequelae in mice surviving high-dose total body irradiation Back to basics: how natural products can provide the basis for new therapeutics.Targeting prostate cancer based on signal transduction and cell cycle pathways.Radiation-induced HIF-1alpha cell survival pathway is inhibited by soy isoflavones in prostate cancer cells.Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.Perspectives on the role of isoflavones in prostate cancer.Role of phytoestrogens in cancer therapy.Simultaneous inhibition of cell-cycle, proliferation, survival, metastatic pathways and induction of apoptosis in breast cancer cells by a phytochemical super-cocktail: genes that underpin its mode of action.Soy isoflavones in conjunction with radiation therapy in patients with prostate cancer

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P2860

Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest

http://www.wikidata.org/entity/Q33241207

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2006 nî lūn-bûn

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Genistein inhibits radiation-i ...... sis and G2/M cell cycle arrest

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Genistein inhibits radiation-i ...... sis and G2/M cell cycle arrest

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Genistein inhibits radiation-i ...... sis and G2/M cell cycle arrest

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Genistein inhibits radiation-i ...... sis and G2/M cell cycle arrest

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Genistein inhibits radiation-i ...... sis and G2/M cell cycle arrest

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Genistein inhibits radiation-i ...... sis and G2/M cell cycle arrest

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Genistein inhibits radiation-i ...... sis and G2/M cell cycle arrest

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Fazlul H Sarkar

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Gilda G Hillman

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Jeffrey D Forman

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Julian J Raffoul

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Omer Kucuk

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Yu Wang

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P2860

Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line

p21 is a universal inhibitor of cyclin kinases

Nuclear factor-kappaB/p65 (Rel A) is constitutively activated in human prostate adenocarcinoma and correlates with disease progression

NF-kappaB in cancer: from innocent bystander to major culprit

Cancer statistics, 2006

Genistein potentiates the radiation effect on prostate carcinoma cells.

Preclinical and clinical development of cyclin-dependent kinase modulators.

Response of cyclin B1 to ionizing radiation: regulation by NF-kappaB and mitochondrial antioxidant enzyme MnSOD.

Role of the NF-kappaB pathway in the pathogenesis of human disease states.

Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells.

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6

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Fazlul H. Sarkar

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