Cationic polyamines inhibit anthrax lethal factor protease
about
Identification of novel non-hydroxamate anthrax toxin lethal factor inhibitors by topomeric searching, docking and scoring, and in vitro screening.High-affinity, human antibody-like antibody fragment (single-chain variable fragment) neutralizing the lethal factor (LF) of Bacillus anthracis by inhibiting protective antigen-LF complex formation.Bacillus anthracis endospores regulate ornithine decarboxylase and inducible nitric oxide synthase through ERK1/2 and p38 mitogen-activated protein kinasesDevelopment of a comprehensive, validated pharmacophore hypothesis for anthrax toxin lethal factor (LF) inhibitors using genetic algorithms, Pareto scoring, and structural biology.Designing inhibitors of anthrax toxinInhibition of anthrax lethal factor: lability of hydroxamate as a chelating groupNew insights into the pathogenesis and treatment of anthrax toxin-induced shock.Potential biological targets of Bacillus anthracis in anti-infective approaches against the threat of bioterrorism.A multifaceted role for polyamines in bacterial pathogens.Small molecule inhibitors of anthrax lethal factor toxinAnti-virulence Strategies to Target Bacterial Infections.Cross-inhibition of pathogenic agents and the host proteins they exploit.Biochemical Features of Beneficial Microbes: Foundations for Therapeutic Microbiology.
P2860
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P2860
Cationic polyamines inhibit anthrax lethal factor protease
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Cationic polyamines inhibit anthrax lethal factor protease
@ast
Cationic polyamines inhibit anthrax lethal factor protease
@en
type
label
Cationic polyamines inhibit anthrax lethal factor protease
@ast
Cationic polyamines inhibit anthrax lethal factor protease
@en
prefLabel
Cationic polyamines inhibit anthrax lethal factor protease
@ast
Cationic polyamines inhibit anthrax lethal factor protease
@en
P2093
P2860
P356
P1433
P1476
Cationic polyamines inhibit anthrax lethal factor protease
@en
P2093
Dominique Nguyen
Lynne Cregar
Mark Evan Goldman
Ondrej Simo
Sean O'Malley
Tom Humphreys
P2860
P2888
P356
10.1186/1471-2210-6-8
P577
2006-06-08T00:00:00Z
P5875
P6179
1052672874