Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia.
about
Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosisCloning and characterization of LUN, a novel ring finger protein that is highly expressed in lung and specifically binds to a palindromic sequencePML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaBCooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancerEvidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infectionsHLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressorAXIN is an essential co-activator for the promyelocytic leukemia protein in p53 activationMolecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatmentLeukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodiesPML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PMLThe solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PMLOncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilizationEvidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger proteinPML, a growth suppressor disrupted in acute promyelocytic leukemiaTRIM family proteins: retroviral restriction and antiviral defenceThe promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damageCoactivator TIF1beta interacts with transcription factor C/EBPbeta and glucocorticoid receptor to induce alpha1-acid glycoprotein gene expression.The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoterViral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruptionEpstein-barr virus immediate-early protein BZLF1 is SUMO-1 modified and disrupts promyelocytic leukemia bodiesA novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory proteinConjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus.TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1Identification and preliminary characterization of a protein motif related to the zinc fingerPLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptorsThe t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcriptRearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemiaThe hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culturePML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemiaAutophagy in malignant transformation and cancer progressionPML is required for telomere stability in non-neoplastic human cellsNovel topology of a zinc-binding domain from a protein involved in regulating early Xenopus developmentThe transcriptional role of PML and the nuclear bodyRing finger in the peroxisome assembly factor-1PML protein isoforms and the RBCC/TRIM motifPhysical and functional interactions between PML and MDM2
P2860
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P2860
Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia.
description
1991 nî lūn-bûn
@nan
1991 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Characterization of a zinc fin ...... acute promyelocytic leukemia.
@ast
Characterization of a zinc fin ...... acute promyelocytic leukemia.
@en
type
label
Characterization of a zinc fin ...... acute promyelocytic leukemia.
@ast
Characterization of a zinc fin ...... acute promyelocytic leukemia.
@en
prefLabel
Characterization of a zinc fin ...... acute promyelocytic leukemia.
@ast
Characterization of a zinc fin ...... acute promyelocytic leukemia.
@en
P2093
P356
P1433
P1476
Characterization of a zinc fin ...... acute promyelocytic leukemia.
@en
P2093
P304
P356
10.1126/SCIENCE.1720570
P407
P577
1991-11-01T00:00:00Z