Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation
about
Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failureTracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4ESumoylation of eIF4E activates mRNA translationPhosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defenseControl of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinaseRibosomal protein S3, a new substrate of Akt, serves as a signal mediator between neuronal apoptosis and DNA repairSignalling to eIF4E in cancermTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsThe circadian clock coordinates ribosome biogenesisAltering chemosensitivity by modulating translation elongationStructural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiationRegulation of translation initiation in eukaryotes: mechanisms and biological targetsIntegrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humansAntitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrolThe sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement.Temporal and spatial regulation of translation in the mammalian oocyte via the mTOR-eIF4F pathwayAn approach to analyse the specific impact of rapamycin on mRNA-ribosome association.Fibrotic myofibroblasts manifest genome-wide derangements of translational controlRole of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inferenceAnalysis of translation using polysome profiling.The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesisEstrogen coordinates translation and transcription, revealing a role for NRSF in human breast cancer cells.HDAC2 promotes eIF4E sumoylation and activates mRNA translation gene specifically.Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development.Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation.Translational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cellsThe translational response of the human mdm2 gene in HEK293T cells exposed to rapamycin: a role for the 5'-UTRs.Distinct translational control in CD4+ T cell subsets.Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombinationPhosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samplesTargeting the eIF4F translation initiation complex: a critical nexus for cancer developmentExpression of truncated eukaryotic initiation factor 3e (eIF3e) resulting from integration of mouse mammary tumor virus (MMTV) causes a shift from cap-dependent to cap-independent translation.eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling.Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescencePoly(A) binding protein abundance regulates eukaryotic translation initiation factor 4F assembly in human cytomegalovirus-infected cells.Eukaryotic Translation Initiation Factor 4E Is a Feed-Forward Translational Coactivator of Transforming Growth Factor β Early Protransforming Events in Breast Epithelial Cells.Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesisTuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner.Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma.
P2860
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P2860
Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Epigenetic activation of a sub ...... effects on cell proliferation
@ast
Epigenetic activation of a sub ...... effects on cell proliferation
@en
Epigenetic activation of a sub ...... effects on cell proliferation.
@nl
type
label
Epigenetic activation of a sub ...... effects on cell proliferation
@ast
Epigenetic activation of a sub ...... effects on cell proliferation
@en
Epigenetic activation of a sub ...... effects on cell proliferation.
@nl
prefLabel
Epigenetic activation of a sub ...... effects on cell proliferation
@ast
Epigenetic activation of a sub ...... effects on cell proliferation
@en
Epigenetic activation of a sub ...... effects on cell proliferation.
@nl
P2093
P2860
P50
P1433
P1476
Epigenetic activation of a sub ...... effects on cell proliferation
@en
P2093
Emmanuel Petroulakis
Taka-Aki Sato
Vinagolu K Rajasekhar
Yaël Mamane
P2860
P356
10.1371/JOURNAL.PONE.0000242
P407
P577
2007-02-21T00:00:00Z