Mechanisms of copper ion mediated Huntington's disease progression
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Metals and NeurodegenerationIron dysregulation in Huntington's diseaseNew perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseasesA novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's diseasePositron emission tomography for measurement of copper fluxes in live organisms.A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system.Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.Copper is an endogenous modulator of neural circuit spontaneous activity.Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein.Iron accumulates in Huntington's disease neurons: protection by deferoxamineNeonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.Iron is a specific cofactor for distinct oxidation- and aggregation-dependent Aβ toxicity mechanisms in a Drosophila model.Thiol-disulfide Oxidoreductases TRX1 and TMX3 Decrease Neuronal Atrophy in a Lentiviral Mouse Model of Huntington's DiseaseAlterations in brain transition metals in Huntington disease: an evolving and intricate story.Mechanism of copper induced fluorescence quenching of red fluorescent protein, DsRedNeonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington's Disease Mice.Proteomics of neural stem cells.Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.Pathology-dependent effects linked to small heat shock proteins expression: an updateNeurotrophic support and oxidative stress: converging effects in the normal and diseased nervous system.Molecular identification of ancient and modern mammalian magnesium transporters.Oxidative Stress and Huntington's Disease: The Good, The Bad, and The Ugly.Mitochondrial metals as a potential therapeutic target in neurodegeneration.Unique effect of Cu(II) in the metal-induced amyloid formation of β-2-microglobulinThe iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders.Transition metal homeostasis: from yeast to human disease.Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases.Role of manganese in neurodegenerative diseases.Copper complexes as therapeutic agents.Copper-dependent regulation of NMDA receptors by cellular prion protein: implications for neurodegenerative disorders.Protein oxidation in Huntington disease.Limbic system pathologies associated with deficiencies and excesses of the trace elements iron, zinc, copper, and selenium.A review of metal-catalyzed molecular damage: protection by melatonin.Characterization of biometal profiles in neurological disorders.Biological metals and metal-targeting compounds in major neurodegenerative diseases.What has fluorescent sensing told us about copper and brain malfunction?The secret life of extracellular vesicles in metal homeostasis and neurodegeneration.Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration.Metallothioneins in Prion- and Amyloid-Related Diseases.
P2860
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P2860
Mechanisms of copper ion mediated Huntington's disease progression
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
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2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mechanisms of copper ion mediated Huntington's disease progression
@ast
Mechanisms of copper ion mediated Huntington's disease progression
@en
Mechanisms of copper ion mediated Huntington's disease progression.
@nl
type
label
Mechanisms of copper ion mediated Huntington's disease progression
@ast
Mechanisms of copper ion mediated Huntington's disease progression
@en
Mechanisms of copper ion mediated Huntington's disease progression.
@nl
prefLabel
Mechanisms of copper ion mediated Huntington's disease progression
@ast
Mechanisms of copper ion mediated Huntington's disease progression
@en
Mechanisms of copper ion mediated Huntington's disease progression.
@nl
P2093
P2860
P50
P1433
P1476
Mechanisms of copper ion mediated Huntington's disease progression
@en
P2093
Gregory Lieberman
Jibrin A Kama
Jonathan H Fox
Kate Dorsey
Raman Chopra
Robert A Cherny
Vanita Chopra
P2860
P356
10.1371/JOURNAL.PONE.0000334
P407
P577
2007-03-28T00:00:00Z