Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction.
about
Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene familyPopulation genetic tools for dissecting innate immunity in humansEvolutionary dynamics of human Toll-like receptors and their different contributions to host defenseAllele-specific induction of IL-1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibilityThe lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humansTLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetesToll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.Two patients with leprosy and the sudden appearance of inflammation in the skin and new sensory loss.Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.Mycobacterium leprae actively modulates the cytokine response in naive human monocytes.Common variants of TLR1 associate with organ dysfunction and sustained pro-inflammatory responses during sepsis.Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states.Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes.Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis.The armadillo: a model for the neuropathy of leprosy and potentially other neurodegenerative diseases.Leprosy and the human genomePolymorphisms in Toll-like receptor 4 (TLR4) are associated with protection against leprosyPARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.Leprosy in the 21st century.Mycobacterium leprae-host-cell interactions and genetic determinants in leprosy: an overview.Human polymorphisms as clinical predictors in leprosyVariants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory diseaseToll-like receptor 1 polymorphisms increase susceptibility to candidemia.Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal.Duration of protective immunity and antibody responses in cattle immunised against alcelaphine herpesvirus-1-induced malignant catarrhal fever.NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy.Cell surface trafficking of TLR1 is differentially regulated by the chaperones PRAT4A and PRAT4B.A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy.Differential trafficking of TLR1 I602S underlies host protection against pathogenic mycobacteria.Mycobacterial signaling through toll-like receptorsA common TLR1 polymorphism is associated with higher parasitaemia in a Southeast Asian population with Plasmodium falciparum malaria.Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity GenesDevelopment of Type 2, But Not Type 1, Leprosy Reactions is Associated with a Severe Reduction of Circulating and In situ Regulatory T-CellsImmune reconstitution reactions in human immunodeficiency virus-negative patients: report of a case and review of the literatureA TLR6 polymorphism is associated with increased risk of Legionnaires' disease.An association study of TOLL and CARD with leprosy susceptibility in Chinese population.Toll-like receptors: their roles in bacterial recognition and respiratory infections.Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.PARK2 and proinflammatory/anti-inflammatory cytokine gene interactions contribute to the susceptibility to leprosy: a case-control study of North Indian population.
P2860
Q24304480-3CEA0236-D296-43C7-AF1A-007A2FCC80F4Q27001032-625363BD-3A71-4F02-9E25-D7C7E4645826Q28252291-58D5AAB9-7AF0-4CB2-A4DB-45A7134F5A49Q28396007-1E9BB193-0F84-4893-B0FF-E5B0C791FADAQ30495582-5CA63EB4-9065-4FEB-8A32-D1C5D2DE6865Q31037925-F099A3E0-020E-4A23-A368-F2271025359AQ33471464-3C82B282-98BB-4257-8978-2C111BBC9020Q33507252-0095F955-384D-4BCC-87B4-655A38DBAD1EQ33519084-250A95A9-0005-4694-90B1-15AF46FAF403Q33557846-318073CA-83D7-4077-BCBF-A94870E4DF8DQ33737424-30294F94-69DC-4EBB-A19D-F016AA94424BQ33785762-F2459483-6A36-41B9-B153-A4F0F454F6EAQ33996621-3FA5A8A7-4B7F-41AB-9FCA-97D01514F89FQ34137717-0DA238C5-68AB-4DAE-B970-3A5298F6418EQ34286974-7AEA9A9F-7CF5-4681-A67F-0B6902258661Q34316512-51EE1F30-7509-4403-A1A4-3728DCF30BFBQ34431856-B142DB14-78A7-4D0D-9D41-59B1DE9604AFQ34470593-69840448-228E-4910-960A-952A1573A638Q34563658-A59A8E53-211A-4D93-8CBA-3278837AC5F8Q34826763-0FCF6DA3-EA71-487B-A02D-41A03DD1446CQ35070041-128ECC7B-2563-4596-BF67-D2EAE1ECE3A1Q35636319-557F69DA-4424-4664-8D98-EAF50732EF9FQ35694671-3127181B-B002-449A-B235-57A8A345E43BQ35765997-0A536B2A-BBB0-412A-A426-B0BD572764B8Q35825015-30D456DE-1C39-4C80-9018-C6EABAF57425Q35927853-FD3BB73B-28B2-43A3-803C-5038D3C374AAQ35948586-B9970EC5-51E1-4A5E-B1BB-C20A4F149337Q35956428-48878E83-D31F-431D-84A7-D8A003E19F54Q36286140-C4877C23-EE29-443A-A33B-CE90F3498F18Q36417345-8DF08857-A13A-4FFB-A77A-8ABBD7FFBCC2Q36419248-636CB482-D351-4FC4-BE88-700658FE1F83Q36439212-6D10058C-DCD5-4732-ADA4-02A7B0C6F99FQ36473385-B722CF96-EA38-4D8B-A05B-9B29F945578FQ36775999-71046D9D-5878-4B41-A6AD-9E9670C9BDDFQ37172390-E92013FC-E68E-4490-9370-60CF2643CEE9Q37216839-5880C19D-4BD4-45D9-81D4-8771BB2C6B47Q37220695-90373F7D-D788-48B8-8080-0FCC1D023000Q37228738-E069640C-0A5B-4732-A1DA-1C2A4FF502AFQ37497786-7C3ED5F8-60D5-4D11-9965-105FF24FC8B6Q37612167-9BEF0DE2-9906-429A-B28F-5E7DBEEDB34A
P2860
Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@ast
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@en
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@nl
type
label
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@ast
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@en
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@nl
prefLabel
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@ast
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@en
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@nl
P2093
P2860
P921
P1476
Human TLR1 deficiency is assoc ...... rom leprosy reversal reaction.
@en
P2093
Bishwa R Sapkota
Chaman Ranjit
Elizabeth A Misch
M Ruby Siddiqui
Murdo Macdonald
Richard D Wells
Thomas R Hawn
P2860
P356
10.1371/JOURNAL.PNTD.0000231
P407
P50
P5008
P577
2008-05-07T00:00:00Z