A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modified vacuoles
about
Antibiotics and UV radiation induce competence for natural transformation in Legionella pneumophilaSubversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila EffectorsActivation of Ran GTPase by a Legionella effector promotes microtubule polymerization, pathogen vacuole motility and infectionPurification and proteomics of pathogen-modified vacuoles and membranesIdentification of another module involved in the horizontal transfer of the Haemophilus genomic island ICEHin1056Biological diversity of prokaryotic type IV secretion systems.Molecular pathogenesis of infections caused by Legionella pneumophilaComprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila.E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substratesThe E Block motif is associated with Legionella pneumophila translocated substrates.Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins.Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins.Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii.The Legionella IcmSW complex directly interacts with DotL to mediate translocation of adaptor-dependent substrates.The Coxiella burnetii cryptic plasmid is enriched in genes encoding type IV secretion system substrates.Reassessing the role of DotF in the Legionella pneumophila type IV secretion systemIn search of Brucella abortus type IV secretion substrates: screening and identification of four proteins translocated into host cells through VirB system.Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion.Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions.Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes.Asc modulates the function of NLRC4 in response to infection of macrophages by Legionella pneumophila.Beyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infectionBacterial type IV secretion systems in human disease.Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors.Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones.A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases.Icm/Dot-dependent inhibition of phagocyte migration by Legionella is antagonized by a translocated Ran GTPase activator.Anaplasma phagocytophilum AptA modulates Erk1/2 signalling.Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane.Comparative Proteomics of Purified Pathogen Vacuoles Correlates Intracellular Replication of Legionella pneumophila with the Small GTPase Ras-related protein 1 (Rap1).Host Kinase Activity is Required for Coxiella burnetii Parasitophorous Vacuole Formation.Novel export control of a Legionella Dot/Icm substrate is mediated by dual, independent signal sequences.Architecture of the type IV coupling protein complex of Legionella pneumophila.Evolution of the Arsenal of Legionella pneumophila Effectors To Modulate Protist Hosts
P2860
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P2860
A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modified vacuoles
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A Legionella pneumophila effec ...... s to Dot/Icm-modified vacuoles
@ast
A Legionella pneumophila effec ...... s to Dot/Icm-modified vacuoles
@en
type
label
A Legionella pneumophila effec ...... s to Dot/Icm-modified vacuoles
@ast
A Legionella pneumophila effec ...... s to Dot/Icm-modified vacuoles
@en
prefLabel
A Legionella pneumophila effec ...... s to Dot/Icm-modified vacuoles
@ast
A Legionella pneumophila effec ...... s to Dot/Icm-modified vacuoles
@en
P2860
P1433
P1476
A Legionella pneumophila effec ...... s to Dot/Icm-modified vacuoles
@en
P2093
Shira Ninio
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000278
P577
2009-01-23T00:00:00Z