A microhomology-mediated break-induced replication model for the origin of human copy number variation.
about
A complex genomic rearrangement involving the endothelin 3 locus causes dermal hyperpigmentation in the chickenThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayMechanisms of gene duplication and amplificationMechanisms of change in gene copy numberCrystal structures of DNA-Whirly complexes and their role in Arabidopsis organelle genome repairMechanisms underlying structural variant formation in genomic disordersGenetic Susceptibility to Rhodococcus equiBiologic and clinical significance of androgen receptor variants in castration resistant prostate cancerRescuing stalled or damaged replication forksStructural variation discovery in the cancer genome using next generation sequencing: computational solutions and perspectivesMAPK pathway activation in pilocytic astrocytomaCNVs: harbingers of a rare variant revolution in psychiatric geneticsGeneration of tandem direct duplications by reversed-ends transposition of maize ac elementsA conserved lysine residue of plant Whirly proteins is necessary for higher order protein assembly and protection against DNA damageStructural variation mutagenesis of the human genome: Impact on disease and evolution.Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknownsBreak-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.A mechanism of gene amplification driven by small DNA fragments.Migrating bubble during break-induced replication drives conservative DNA synthesis.Replication fork instability and the consequences of fork collisions from rereplicationNoncanonical views of homology-directed DNA repairRAD51 mutants cause replication defects and chromosomal instabilityGJB1/Connexin 32 whole gene deletions in patients with X-linked Charcot-Marie-Tooth disease.Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromesSomatic mosaicism underlies X-linked acrogigantism syndrome in sporadic male subjectsFrequent Somatic Mutation in Adult Intestinal Stem Cells Drives Neoplasia and Genetic Mosaicism during AgingIntrachromosomal amplification, locus deletion and point mutation in the aquaglyceroporin AQP1 gene in antimony resistant Leishmania (Viannia) guyanensisInteraction-based evolution: how natural selection and nonrandom mutation work togetherLandscape of somatic retrotransposition in human cancersAluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.The role of combined SNV and CNV burden in patients with distal symmetric polyneuropathy.Mechanisms for Structural Variation in the Human GenomeA novel in-frame deletion affecting the BAR domain of OPHN1 in a family with intellectual disability and hippocampal alterations.PacBio-LITS: a large-insert targeted sequencing method for characterization of human disease-associated chromosomal structural variationsBreakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.Characterizing complex structural variation in germline and somatic genomesComplex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integrationGenome-wide mapping and assembly of structural variant breakpoints in the mouse genomeShort template switch events explain mutation clusters in the human genome.Mechanisms of chromosomal rearrangement in the human genome
P2860
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P2860
A microhomology-mediated break-induced replication model for the origin of human copy number variation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A microhomology-mediated break ...... f human copy number variation.
@ast
A microhomology-mediated break ...... f human copy number variation.
@en
type
label
A microhomology-mediated break ...... f human copy number variation.
@ast
A microhomology-mediated break ...... f human copy number variation.
@en
prefLabel
A microhomology-mediated break ...... f human copy number variation.
@ast
A microhomology-mediated break ...... f human copy number variation.
@en
P2093
P2860
P1433
P1476
A microhomology-mediated break ...... f human copy number variation.
@en
P2093
Grzegorz Ira
James R Lupski
P J Hastings
P2860
P304
P356
10.1371/JOURNAL.PGEN.1000327
P577
2009-01-01T00:00:00Z
2009-01-30T00:00:00Z