Sand fly salivary proteins induce strong cellular immunity in a natural reservoir of visceral leishmaniasis with adverse consequences for Leishmania. - sprookjes - yvandenbroek - TriplyDB

Sand fly salivary proteins induce strong cellular immunity in a natural reservoir of visceral leishmaniasis with adverse consequences for Leishmania.

Sand fly salivary proteins induce strong cellular immunity in a natural reservoir of visceral leishmaniasis with adverse consequences for Leishmania.

http://www.wikidata.org/entity/Q33450546

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Is arthropod saliva the achilles' heel of vector-borne diseases?Lutzomyia longipalpis saliva or salivary protein LJM19 protects against Leishmania braziliensis and the saliva of its vector, Lutzomyia intermedia What's behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity Sand fly-Leishmania interactions: long relationships are not necessarily easy Texas and Mexico: sharing a legacy of poverty and neglected tropical diseases Vaccines for the leishmaniases: proposals for a research agenda Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis The Diversity of Yellow-Related Proteins in Sand Flies (Diptera: Psychodidae).Vaccines to combat the neglected tropical diseases.Human cellular immune response to the saliva of Phlebotomus papatasi is mediated by IL-10-producing CD8+ T cells and Th1-polarized CD4+ lymphocytes Seroconversion to Lutzomyia intermedia LinB-13 as a biomarker for developing cutaneous leishmaniasis.Leishmaniasis Vaccine: Where are We Today?Vector saliva in vaccines for visceral leishmaniasis: a brief encounter of high consequence?Expression plasticity of Phlebotomus papatasi salivary gland genes in distinct ecotopes through the sand fly season Canine antibody response to Phlebotomus perniciosus bites negatively correlates with the risk of Leishmania infantum transmission.Visceral Leishmaniasis: Advancements in Vaccine Development via Classical and Molecular Approaches Salivary gland transcriptomes and proteomes of Phlebotomus tobbi and Phlebotomus sergenti, vectors of leishmaniasis.Kinetics of antibody response in BALB/c and C57BL/6 mice bitten by Phlebotomus papatasi.Updating the salivary gland transcriptome of Phlebotomus papatasi (Tunisian strain): the search for sand fly-secreted immunogenic proteins for humans.Salivary antigen SP32 is the immunodominant target of the antibody response to Phlebotomus papatasi bites in humans.Experimental infection of dogs with Leishmania and saliva as a model to study Canine Visceral Leishmaniasis.Severity of old world cutaneous leishmaniasis is influenced by previous exposure to sandfly bites in Saudi Arabia Comparative analysis of salivary gland transcriptomes of Phlebotomus orientalis sand flies from endemic and non-endemic foci of visceral leishmaniasis.Development of Vaccines against Visceral Leishmaniasis Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection Meta-analysis of the effects of insect vector saliva on host immune responses and infection of vector-transmitted pathogens: a focus on leishmaniasis.No recent adaptive selection on the apyrase of Mediterranean Phlebotomus: implications for using salivary peptides to vaccinate against canine leishmaniasis.Phlebotomus papatasi SP15: mRNA expression variability and amino acid sequence polymorphisms of field populations Validation of Recombinant Salivary Protein PpSP32 as a Suitable Marker of Human Exposure to Phlebotomus papatasi, the Vector of Leishmania major in Tunisia New Insights on the Inflammatory Role of Lutzomyia longipalpis Saliva in Leishmaniasis Expression, purification, crystallization and crystallographic study of Lutzomyia longipalpis LJL143.Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters.The immune response to sand fly salivary proteins and its influence on leishmania immunity Interleukin 10-Dominant Immune Response and Increased Risk of Cutaneous Leishmaniasis After Natural Exposure to Lutzomyia intermedia Sand Flies.Biomarkers for exposure to sand flies bites as tools to aid control of leishmaniasis.Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.The protein LJM 111 from Lutzomyia longipalpis salivary gland extract (SGE) accounts for the SGE-inhibitory effects upon inflammatory parameters in experimental arthritis model.Immunity to sand fly salivary protein LJM11 modulates host response to vector-transmitted leishmania conferring ulcer-free protection.Delayed-type hypersensitivity to sand fly saliva in humans from a leishmaniasis-endemic area of Mali is Th1-mediated and persists to midlife.SALO, a novel classical pathway complement inhibitor from saliva of the sand fly Lutzomyia longipalpis.

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P2860

Sand fly salivary proteins induce strong cellular immunity in a natural reservoir of visceral leishmaniasis with adverse consequences for Leishmania.

http://www.wikidata.org/entity/Q33450546

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2009 nî lūn-bûn

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Sand fly salivary proteins ind ...... e consequences for Leishmania.

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Sand fly salivary proteins ind ...... e consequences for Leishmania.

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Andre Laughinghouse

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Clarissa Teixeira

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Dia-Eldin Elnaiem

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Jerrold M Ward

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Jesus G Valenzuela

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Laurent Fischer

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Lily Cheng

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Nicolas Collin

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Regis Gomes

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Shaden Kamhawi

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P2860

Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi.

Spread of vector-borne diseases and neglect of Leishmaniasis, Europe.

From transcriptome to immunome: identification of DTH inducing proteins from a Phlebotomus ariasi salivary gland cDNA library.

Immunity to distinct sand fly salivary proteins primes the anti-Leishmania immune response towards protection or exacerbation of disease.

Leishmune vaccine blocks the transmission of canine visceral leishmaniasis: absence of Leishmania parasites in blood, skin and lymph nodes of vaccinated exposed dogs.

Safety trial using the Leishmune vaccine against canine visceral leishmaniasis in Brazil.

Vaccines for leishmaniasis in the fore coming 25 years.

The immunology of susceptibility and resistance to Leishmania major in mice.

Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein.

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