Dissecting structural and functional diversity of the lantibiotic mersacidin
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Discovery and Development of NVB302, a Semisynthetic Antibiotic for Treatment of Clostridium difficile InfectionLanthipeptides: chemical synthesis versus in vivo biosynthesis as tools for pharmaceutical productionBioengineering Lantibiotics for Therapeutic SuccessType AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of actionExpression of the lantibiotic mersacidin in Bacillus amyloliquefaciens FZB42Identification, purification and characterization of laterosporulin, a novel bacteriocin produced by Brevibacillus sp. strain GI-9Bioengineered nisin A derivatives with enhanced activity against both Gram positive and Gram negative pathogensA bioengineered nisin derivative to control biofilms of Staphylococcus pseudintermediusExpansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor familySonorensin: an antimicrobial peptide, belonging to the heterocycloanthracin subfamily of bacteriocins, from a new marine isolate, Bacillus sonorensis MT93.Synthesis of trypsin-resistant variants of the Listeria-active bacteriocin salivaricin PRibosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.Codon randomization for rapid exploration of chemical space in thiopeptide antibiotic variants.Investigating the importance of charged residues in lantibiotics.A price to pay for relaxed substrate specificity: a comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2.Characterization of amylolysin, a novel lantibiotic from Bacillus amyloliquefaciens GA1.Homologues and bioengineered derivatives of LtnJ vary in ability to form D-alanine in the lantibiotic lacticin 3147.Leader Peptide Establishes Dehydration Order, Promotes Efficiency, and Ensures Fidelity During Lacticin 481 Biosynthesis.Engineering unnatural variants of plantazolicin through codon reprogramming.Follow the leader: the use of leader peptides to guide natural product biosynthesis.Ribosomally synthesized and post-translationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis.Draft Genome Sequence of Staphylococcus simulans UMC-CNS-990, Isolated from a Case of Chronic Bovine Mastitis.Saturation mutagenesis of selected residues of the α-peptide of the lantibiotic lacticin 3147 yields a derivative with enhanced antimicrobial activityFundamental functionality: recent developments in understanding the structure-activity relationships of lantibiotic peptides.The dawning of a 'Golden era' in lantibiotic bioengineering.Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development.The challenge of the lantibiotics: synthetic approaches to thioether-bridged peptides.Advances in the arsenal of tools available enabling the discovery of novel lantibiotics with therapeutic potential.Multipronged approach for engineering novel peptide analogues of existing lantibiotics.Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.Cysteine-rich low molecular weight antimicrobial peptides from Brevibacillus and related genera for biotechnological applications.Bioengineering: a bacteriocin perspective.In Vitro Biosynthesis and Substrate Tolerance of the Plantazolicin Family of Natural Products.Synthesis of the AviMeCys-containing D-ring of mersacidin.Organization of the biosynthetic genes encoding deoxyactagardine B (DAB), a new lantibiotic produced by Actinoplanes liguriae NCIMB41362.Perspectives on lantibiotic discovery - where have we failed and what improvements are required?Fighting biofilms with lantibiotics and other groups of bacteriocins.
P2860
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P2860
Dissecting structural and functional diversity of the lantibiotic mersacidin
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Dissecting structural and functional diversity of the lantibiotic mersacidin
@ast
Dissecting structural and functional diversity of the lantibiotic mersacidin
@en
type
label
Dissecting structural and functional diversity of the lantibiotic mersacidin
@ast
Dissecting structural and functional diversity of the lantibiotic mersacidin
@en
prefLabel
Dissecting structural and functional diversity of the lantibiotic mersacidin
@ast
Dissecting structural and functional diversity of the lantibiotic mersacidin
@en
P2093
P2860
P1476
Dissecting structural and functional diversity of the lantibiotic mersacidin
@en
P2093
Anja Hoffmann
Ann Lightfoot
Antony N Appleyard
Brian A M Rudd
Daniel M Read
Gabriele Bierbaum
Ian Chopra
Jesus Cortes
Shaila Choi
Steven Boakes
P2860
P304
P356
10.1016/J.CHEMBIOL.2009.03.011
P577
2009-05-01T00:00:00Z