Vpu matchmakers as a therapeutic strategy for HIV infection.
about
Novel approaches to inhibiting HIV-1 replication.Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.Polarity changes in the transmembrane domain core of HIV-1 Vpu inhibits its anti-tetherin activity.Viral replication is enhanced by an HIV-1 intersubtype recombination-derived Vpu protein.Oligomerization state and supramolecular structure of the HIV-1 Vpu protein transmembrane segment in phospholipid bilayersIdentification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility.Ion channels as antivirus targets.Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue.A novel peptide to disrupt the interaction of BST-2 and Vpu.Overexpression of inactive tetherin delGPI mutant inhibits HIV-1 Vpu-mediated antagonism of endogenous tetherin.
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P2860
Vpu matchmakers as a therapeutic strategy for HIV infection.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Vpu matchmakers as a therapeutic strategy for HIV infection.
@ast
Vpu matchmakers as a therapeutic strategy for HIV infection.
@en
type
label
Vpu matchmakers as a therapeutic strategy for HIV infection.
@ast
Vpu matchmakers as a therapeutic strategy for HIV infection.
@en
prefLabel
Vpu matchmakers as a therapeutic strategy for HIV infection.
@ast
Vpu matchmakers as a therapeutic strategy for HIV infection.
@en
P2860
P1433
P1476
Vpu matchmakers as a therapeutic strategy for HIV infection.
@en
P2093
Mauricio Montal
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000246
P577
2009-05-29T00:00:00Z