Interrogating and predicting tolerated sequence diversity in protein folds: application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein

Interrogating and predicting tolerated sequence diversity in protein folds: application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein

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http://www.wikidata.org/entity/Q33500130
Cystine-knot peptides engineered with specificities for α(IIb)β(3) or α(IIb)β(3) and α(v)β(3) integrins are potent inhibitors of platelet aggregation.Functional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein.Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).CNS Anticancer Drug Discovery and Development Conference White Paper.Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.99mTc-labeled cystine knot peptide targeting integrin αvβ6 for tumor SPECT imaging.Engineered cystine-knot miniproteins for diagnostic applications.Plant cystine-knot peptides: pharmacological perspectives.Preliminary evaluation of (177)Lu-labeled knottin peptides for integrin receptor-targeted radionuclide therapy.Membrane topology and identification of critical amino acid residues in the Wzx O-antigen translocase from Escherichia coli O157:H4.
P2860

Interrogating and predicting tolerated sequence diversity in protein folds: application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein

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http://www.wikidata.org/entity/Q33500130
description
2009 nî lūn-bûn
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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Interrogating and predicting t ...... or-II cystine-knot miniprotein
@ast
Interrogating and predicting t ...... or-II cystine-knot miniprotein
@en
type
label
Interrogating and predicting t ...... or-II cystine-knot miniprotein
@ast
Interrogating and predicting t ...... or-II cystine-knot miniprotein
@en
prefLabel
Interrogating and predicting t ...... or-II cystine-knot miniprotein
@ast
Interrogating and predicting t ...... or-II cystine-knot miniprotein
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Interrogating and predicting t ...... or-II cystine-knot miniprotein
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PCBI.1000499
P433
P478
P577
P5875
P698
P921
P932