Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice.
about
Pharmacokinetics and Toxicity in Rats and Monkeys of coDbait: A Therapeutic Double-stranded DNA Oligonucleotide Conjugated to CholesterolSynthetic oligonucleotides: the development of antisense therapeutics.Correlation of toxicity and pharmacokinetic properties of a phosphorothioate oligonucleotide designed to inhibit ICAM-1.Early development of the Toll-like receptor 9 agonist, PF-3512676, for the treatment of patients with advanced cancers.Antisense oligonucleotides as therapeutics for hyperlipidaemias.Methods of evaluating immunotoxicity.Antiinfective applications of toll-like receptor 9 agonists.Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation.Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice.5'-,3'-inverted thymidine-modified antisense oligodeoxynucleotide targeting midkine. Its design and application for cancer therapy.Transcription factor decoy: a pre-transcriptional approach for gene downregulation purpose in cancer.Immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics.Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.Cytosolic delivery of antisense oligonucleotides by listeriolysin O-containing liposomes.CpG and Non-CpG oligodeoxynucleotides induce differential proinflammatory gene expression profiles in liver and peripheral blood leukocytes in mice.Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia.Aptamer Therapeutics in Cancer: Current and Future.Brief communication: stability and catalytic activity of novel circular DNAzymes.
P2860
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P2860
Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Evaluation of the toxicity of ...... n a 4-week study in CD-1 mice.
@ast
Evaluation of the toxicity of ...... n a 4-week study in CD-1 mice.
@en
type
label
Evaluation of the toxicity of ...... n a 4-week study in CD-1 mice.
@ast
Evaluation of the toxicity of ...... n a 4-week study in CD-1 mice.
@en
prefLabel
Evaluation of the toxicity of ...... n a 4-week study in CD-1 mice.
@ast
Evaluation of the toxicity of ...... n a 4-week study in CD-1 mice.
@en
P2093
P356
P1433
P1476
Evaluation of the toxicity of ...... n a 4-week study in CD-1 mice.
@en
P2093
P304
P356
10.1089/OLI.1.1997.7.473
P577
1997-10-01T00:00:00Z