Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin.
about
Streamlined syntheses of (-)-dictyostatin, 16-desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-desmethyl-25,26-dihydrodictyostatinDesign and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activityNatural products from the Lithistida: a review of the literature since 2000.Efficient syntheses of 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, two potent new microtubule-stabilizing agents.Conformation-activity relationships of polyketide natural products.A highly step-economical synthesis of dictyostatin.The Lithistida: important sources of compounds useful in biomedical research.Advances in the development of hybrid anticancer drugs.Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.Ferrocenyl Paclitaxel and Docetaxel Derivatives: Impact of an Organometallic Moiety on the Mode of Action of Taxanes.Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.Highly Stereoselective Total Synthesis of (+)-9-epi-Dictyostatin and (-)-12,13-Bis-epi-dictyostatin
P2860
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P2860
Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Total synthesis of a library o ...... scodermolide and dictyostatin.
@ast
Total synthesis of a library o ...... scodermolide and dictyostatin.
@en
Total synthesis of a library o ...... scodermolide and dictyostatin.
@nl
type
label
Total synthesis of a library o ...... scodermolide and dictyostatin.
@ast
Total synthesis of a library o ...... scodermolide and dictyostatin.
@en
Total synthesis of a library o ...... scodermolide and dictyostatin.
@nl
prefLabel
Total synthesis of a library o ...... scodermolide and dictyostatin.
@ast
Total synthesis of a library o ...... scodermolide and dictyostatin.
@en
Total synthesis of a library o ...... scodermolide and dictyostatin.
@nl
P2093
P2860
P356
P1476
Total synthesis of a library o ...... scodermolide and dictyostatin.
@en
P2093
Amy E Wright
Esther Guzmán
Guy J Naylor
Ian Paterson
P2860
P304
P356
10.1039/B921237J
P407
P577
2009-11-24T00:00:00Z