The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair.
about
Xeroderma pigmentosumTranscription Blockage Leads to New BeginningsClose encounters for the first time: Helicase interactions with DNA damagePathways for repairing and tolerating the spectrum of oxidative DNA lesionsStructure of (5′ S )-8,5′-Cyclo-2′-deoxyguanosine in DNAStructures of (5′ S )-8,5′-Cyclo-2′-deoxyguanosine Mismatched with dA or dTMitochondrial DNA damage induced autophagy, cell death, and diseaseCaenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivoGeneration of guanine-amino acid cross-links by a free radical combination mechanismThe role of XPC: implications in cancer and oxidative DNA damageAge-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathologyNeurotoxic mechanisms of DNA damage: focus on transcriptional inhibition.Spotlight on 'xeroderma pigmentosum'.Impact of age-associated cyclopurine lesions on DNA repair helicases.A 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase βHistopathology of the inner ear in patients with xeroderma pigmentosum and neurologic degeneration.(5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and is inefficiently repaired in Escherichia coliSlow accumulation of mutations in Xpc-/- mice upon induction of oxidative stress.Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.Removal of reactive oxygen species-induced 3'-blocked ends by XPF-ERCC1.Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways.Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient miceBypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks.Accurate and efficient bypass of 8,5'-cyclopurine-2'-deoxynucleosides by human and yeast DNA polymerase η.Hearing Dysfunction in Xpa-Deficient Mice.Stability of N-glycosidic bond of (5'S)-8,5'-cyclo-2'-deoxyguanosine.A quantitative assay for assessing the effects of DNA lesions on transcriptionDifferences in the Access of Lesions to the Nucleotide Excision Repair Machinery in Nucleosomes.Mitochondria as a target of environmental toxicants.Bidirectional transcription of trinucleotide repeats: roles for excision repair.Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ.DNA repair deficiency and neurological disease.Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replication of (5'S)-8,5'-cyclopurine-2'-deoxynucleosides in vitro by DNA polymerase IV, exo-free Klenow fragment, and Dpo4.Neurodegeneration-associated instability of ribosomal DNA.Synthesis of [1,3, NH2-(15)N3] (5'S)-8,5'-cyclo-2'-deoxyguanosineERCC1: impact in multimodality treatment of upper gastrointestinal cancer.Purine 5',8-cyclonucleoside lesions: chemistry and biology.Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody.Repair efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine depends on the complementary base.Transcriptional consequences of XPA disruption in human cell lines.
P2860
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P2860
The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@ast
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@en
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@nl
type
label
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@ast
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@en
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@nl
prefLabel
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@ast
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@en
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@nl
P2860
P1433
P1476
The 8,5'-cyclopurine-2'-deoxyn ...... nd nucleotide excision repair.
@en
P2093
P J Brooks
P2860
P304
P356
10.1016/J.DNAREP.2008.03.016
P577
2008-05-20T00:00:00Z