Targeting the proteolytic processing of the viral glycoprotein precursor is a promising novel antiviral strategy against arenaviruses.
about
A key enzyme in the biogenesis of lysosomes is a protease that regulates cholesterol metabolismArenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategiesEnvelope glycoprotein of arenavirusesProgress in the experimental therapy of severe arenaviral infectionsBiochemical reconstitution of hemorrhagic-fever arenavirus envelope glycoprotein-mediated membrane fusionInsulin degrading enzyme induces a conformational change in varicella-zoster virus gE, and enhances virus infectivity and stabilityNovel approaches in anti-arenaviral drug developmentOld world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transportEvolution of recombinant lymphocytic choriomeningitis virus/Lassa virus in vivo highlights the importance of the GPC cytosolic tail in viral fitness.Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease.Role of the host cell's unfolded protein response in arenavirus infection.Molecular mechanism of arenavirus assembly and budding.Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242.Molecular characterization of the processing of arenavirus envelope glycoprotein precursors by subtilisin kexin isozyme-1/site-1 protease.A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 ProteaseMechanism of Folding and Activation of Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P).Differential recognition of Old World and New World arenavirus envelope glycoproteins by subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P).Tropism of CPMV to Professional Antigen Presenting Cells Enables a Platform to Eliminate Chronic Infections.25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation.Developments in antivirals against influenza, smallpox and hemorrhagic fever viruses.Lymphocytic choriomeningitis virus (LCMV) infection of macaques: a model for Lassa fever.On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications.Current drug discovery strategies against arenavirus infections.Targeting virulence mechanisms for the prevention and therapy of arenaviral hemorrhagic fever.Novel drug discovery approaches for treating arenavirus infections.Herpes simplex virus requires poly(ADP-ribose) polymerase activity for efficient replication and induces extracellular signal-related kinase-dependent phosphorylation and ICP0-dependent nuclear localization of tankyrase 1.Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses.Arenaviruses: Hemorrhagic Fevers
P2860
Q24308865-6BB79123-3790-4A92-A0FF-8F638630C400Q24599295-E0B29F13-E88D-4046-BDB4-332DAFAA2848Q24613392-C92172FB-798D-4695-8CB5-1A8F94E44D16Q27024953-B6787F62-5FC3-4847-B742-3F4C559430FEQ28485416-35290FEC-B8A5-4444-A740-6FA6E3EFECC0Q33622464-C78D88A6-2658-4D36-A698-38A89D02DB15Q33779739-F7FE2F70-677C-44A0-B79F-CEED4A6E47B9Q34023003-291272E1-17A7-4AF4-9D24-F4B5780FFF7FQ34057974-4C42DC7C-1492-4322-8858-C8D9FBA3216BQ34485294-07F5EA3A-8564-4E0D-B84E-B94DBA64EA72Q34529827-921D4B6F-F601-4A8F-9EFF-E4AB95A8854DQ34645914-58530F62-202F-4AA8-9459-8B60E4157654Q34677940-5B6080FD-41F5-4A86-8DB0-5587D8BAE77CQ35774829-9227F3DD-CB79-44B2-A762-052E6F17DE51Q35943805-F5E1A031-FA89-4378-985F-DC067877ED58Q36434299-5944C405-5545-4FCA-BC20-36193B599DD8Q36518221-C22F6981-D62E-4510-B17F-6B40AF6C439DQ36827122-76EAF448-6176-409E-919F-79A13676D989Q36973311-7798698B-707B-483F-8FF7-445DD218385AQ37530422-454A6DE3-01BC-4C85-BAD4-C580A36F00A7Q37828538-A9DC5188-1886-40B9-B27C-A50AF2FF41EAQ37912497-B19AB36B-A070-46B7-9268-C238DB8160F9Q37981645-B9DC75E4-2C9C-47B0-9724-B3B07BEB12C1Q38067504-E313B73B-9B8C-4DA7-B967-EF3187EAF1D2Q38069359-48308187-CC0A-415E-98A1-A708B558100EQ38735837-5E19B177-0C9B-4E45-A36F-51F20C603697Q39455618-C3B59461-EA18-4FCF-99DA-8DD4126FEEAAQ55306089-3576D83A-FD05-4CA4-89AB-33FB17AEEE67Q56763187-7E393926-9B4E-4B68-AD65-56007B78DB4D
P2860
Targeting the proteolytic processing of the viral glycoprotein precursor is a promising novel antiviral strategy against arenaviruses.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Targeting the proteolytic proc ...... strategy against arenaviruses.
@ast
Targeting the proteolytic proc ...... strategy against arenaviruses.
@en
Targeting the proteolytic proc ...... strategy against arenaviruses.
@nl
type
label
Targeting the proteolytic proc ...... strategy against arenaviruses.
@ast
Targeting the proteolytic proc ...... strategy against arenaviruses.
@en
Targeting the proteolytic proc ...... strategy against arenaviruses.
@nl
prefLabel
Targeting the proteolytic proc ...... strategy against arenaviruses.
@ast
Targeting the proteolytic proc ...... strategy against arenaviruses.
@en
Targeting the proteolytic proc ...... strategy against arenaviruses.
@nl
P2093
P2860
P356
P1433
P1476
Targeting the proteolytic proc ...... strategy against arenaviruses.
@en
P2093
Ana B Sanchez
Jillian M Rojek
Juan-Carlos de la Torre
Ngoc-Thao Nguyen
P2860
P304
P356
10.1128/JVI.01697-09
P577
2010-01-01T00:00:00Z