Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway
about
Preclinical evidences toward the use of triterpenoid CDDO-Me for solid cancer prevention and treatmentInhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells.Therapeutic modulators of STAT signalling for human diseasesPrevention of multidrug resistance (MDR) in osteosarcoma by NSC23925.High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenesCorrelation between ERK1 and STAT3 expression and chemoresistance in patients with conventional osteosarcoma.Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties.Clinical and biological significance of PIM1 kinase in osteosarcoma.The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell linesBardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.A Natural Combination Extract of Viscum album L. Containing Both Triterpene Acids and Lectins Is Highly Effective against AML In Vivo.Nanoparticle delivery of CDDO-Me remodels the tumor microenvironment and enhances vaccine therapy for melanoma.Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing SarcomaSynthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cellsThe triterpenoid CDDO-Me promotes hematopoietic progenitor expansion and myelopoiesis in mice.Targeting protein kinases to reverse multidrug resistance in sarcoma.Alternol, a natural compound, exerts an anti-tumour effect on osteosarcoma by modulating of STAT3 and ROS/MAPK signalling pathways.Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy.Blocking the peroxisome proliferator-activated receptor (PPAR): an overview.Synthesis and evaluation of the anticancer activity of albiziabioside A and its analogues as apoptosis inducers against human melanoma cells.Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines.SC-1, a sorafenib derivative, shows anti-tumor effects in osteogenic sarcoma cells.Synergistic Antitumour Properties of viscumTT in Alveolar RhabdomyosarcomaCytotoxic effect of a family of peroxisome proliferator-activated receptor antagonists in colorectal and pancreatic cancer cell lines.Identification and analysis of key genes in osteosarcoma using bioinformatics.GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway.Synergistic effect of ursodeoxycholic acid on the antitumor activity of sorafenib in hepatocellular carcinoma cells via modulation of STAT3 and ERK
P2860
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P2860
Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Oleanane triterpenoid CDDO-Me ...... gh inhibition of Stat3 pathway
@ast
Oleanane triterpenoid CDDO-Me ...... gh inhibition of Stat3 pathway
@en
Oleanane triterpenoid CDDO-Me ...... h inhibition of Stat3 pathway.
@nl
type
label
Oleanane triterpenoid CDDO-Me ...... gh inhibition of Stat3 pathway
@ast
Oleanane triterpenoid CDDO-Me ...... gh inhibition of Stat3 pathway
@en
Oleanane triterpenoid CDDO-Me ...... h inhibition of Stat3 pathway.
@nl
prefLabel
Oleanane triterpenoid CDDO-Me ...... gh inhibition of Stat3 pathway
@ast
Oleanane triterpenoid CDDO-Me ...... gh inhibition of Stat3 pathway
@en
Oleanane triterpenoid CDDO-Me ...... h inhibition of Stat3 pathway.
@nl
P2093
P2860
P356
P1433
P1476
Oleanane triterpenoid CDDO-Me ...... gh inhibition of Stat3 pathway
@en
P2093
Francis J Hornicek
Henry J Mankin
Keinosuke Ryu
Michiro Susa
P2860
P2888
P356
10.1186/1471-2407-10-187
P407
P577
2010-05-10T00:00:00Z
P5875
P6179
1022818809