Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.
about
T Cell Adolescence: Maturation Events Beyond Positive SelectionPak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral TolerancePak2 Controls Acquisition of NKT Cell Fate by Regulating Expression of the Transcription Factors PLZF and Egr2.p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix.Thymic exosomes promote the final maturation of thymocytes.A second generation SNP and SSR integrated linkage map and QTL mapping for the Chinese mitten crab Eriocheir sinensis.Requirement of Treg-intrinsic CTLA4/PKCη signaling pathway for suppressing tumor immunity.Pak2 is essential for the function of Foxp3+ regulatory T cells through maintaining a suppressive Treg phenotype.P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells.Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.Pak2 regulates myeloid-derived suppressor cell development in mice
P2860
Q26800949-0255C6AE-6FDD-46B6-9E4A-CC46F470A86CQ33421593-9D6B38C3-1E6F-44F2-B03C-727B195CEA3CQ35931571-ED716924-6CC6-4BBC-99B3-F603FF51C77BQ36302397-C0E7CE8D-1ED0-47A6-9664-D8240A837994Q36825803-D70F2B03-BB60-450A-84A7-9B73550A1218Q37400141-D26385A5-9CF9-4003-A7F7-4446CA046AA5Q37550171-341558E7-DACE-4B45-9CC4-211ECF6880E3Q46909626-266FAB4D-F896-497A-AA9C-680905FF53ECQ47171646-2A57061B-457E-4805-B510-6823E522406EQ48317168-C9FDE77C-6468-4D78-8483-8D93326D89D4Q52431415-82435FC8-1E7A-452B-AB13-CB890CF5ABE9Q57980065-8160E177-D416-4957-AD83-93ED65B0430D
P2860
Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Pak2 is required for actin cyt ...... te development and maturation.
@ast
Pak2 is required for actin cyt ...... te development and maturation.
@en
type
label
Pak2 is required for actin cyt ...... te development and maturation.
@ast
Pak2 is required for actin cyt ...... te development and maturation.
@en
prefLabel
Pak2 is required for actin cyt ...... te development and maturation.
@ast
Pak2 is required for actin cyt ...... te development and maturation.
@en
P2093
P2860
P50
P356
P1433
P1476
Pak2 is required for actin cyt ...... te development and maturation.
@en
P2093
Debra Cheng
Maria Radu
Marianne Mollenauer
Olga Pryshchep
Rachelle Kosoff
Stephanie Grace Fairbairn
P2860
P304
P356
10.7554/ELIFE.02270
P407
P577
2014-05-13T00:00:00Z