Symplekin promotes tumorigenicity by up-regulating claudin-2 expression - sprookjes - yvandenbroek - TriplyDB

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

http://www.wikidata.org/entity/Q33664419

about

The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4 Claudin-14 regulates renal Ca⁺⁺ transport in response to CaSR signalling via a novel microRNA pathway Alterations of the apical junctional complex and actin cytoskeleton and their role in colorectal cancer progression Paradigms lost-an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesis Transcriptional regulators of claudins in epithelial tight junctions Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis.Interactions of CstF-64, CstF-77, and symplekin: implications on localisation and function.Claudin-4 deficiency results in urothelial hyperplasia and lethal hydronephrosis.Salmonella infection upregulates the leaky protein claudin-2 in intestinal epithelial cells Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine.Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis.Phosphorylation of claudin-2 on serine 208 promotes membrane retention and reduces trafficking to lysosomes Myofibroblast keratinocyte growth factor reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells.Alterations in polyadenylation and its implications for endocrine disease.MicroRNA regulation in renal pathophysiology Cell transcriptional state alters genomic patterns of DNA double-strand break repair in human astrocytes.Mechanism of cytotoxic action of crambescidin-816 on human liver-derived tumour cells.Claudin family of proteins and cancer: an overview.Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment.Enterocytes' tight junctions: From molecules to diseases Rho GTPase signaling in the development of colorectal cancer.Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes.Symplekin specifies mitotic fidelity by supporting microtubule dynamics.Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions.Overexpressed HSF1 cancer signature genes cluster in human chromosome 8q.Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction.

P2860

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P2860

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

http://www.wikidata.org/entity/Q33664419

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

@ast

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

@en

type

label

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

@ast

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

@en

prefLabel

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

@ast

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

@en

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PNAS.0903747107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

@en

P2093

André Pélegrin

http://www.w3.org/2001/XMLSchema#string

Caroline Bonnans

http://www.w3.org/2001/XMLSchema#string

Dominique Joubert

http://www.w3.org/2001/XMLSchema#string

Frédéric Hollande

http://www.w3.org/2001/XMLSchema#string

Jean-François Bourgaux

http://www.w3.org/2001/XMLSchema#string

Marina Papin

http://www.w3.org/2001/XMLSchema#string

Michael Buchert

http://www.w3.org/2001/XMLSchema#string

Véronique Garambois

http://www.w3.org/2001/XMLSchema#string

P2860

Symplekin, a novel type of tight junction plaque protein

Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAs

Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA

Complex protein interactions within the human polyadenylation machinery identify a novel component

Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA

HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin

Multifunctional strands in tight junctions

Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

Differential expression of claudin-2 along the human intestine: Implication of GATA-4 in the maintenance of claudin-2 in differentiating cells

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2628-2633

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scholarly article

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10.1073/PNAS.0903747107

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P433

6

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107

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Julie Pannequin

P577

2010-01-25T00:00:00Z

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41408657

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20133805

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2823888

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