Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1.
about
Accessing DNA damage in chromatin: Preparing the chromatin landscape for base excision repairNucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repairInsights into the glycosylase search for damage from single-molecule fluorescence microscopy.Base excision repair: a critical player in many gamesNucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damagesImpact of abasic site orientation within nucleosomes on human APE1 endonuclease activity.The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structuresBase excision repair of 8-oxoG in dinucleosomes.FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC.Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase.Efficient cleavage of single and clustered AP site lesions within mono-nucleosome templates by CHO-K1 nuclear extract contrasts with retardation of incision by purified APE1.Rules of engagement for base excision repair in chromatinFacilitation of base excision repair by chromatin remodeling.Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes.Repair efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine depends on the complementary base.Design, synthesis, and characterization of nucleosomes containing site-specific DNA damageHuman cells contain a factor that facilitates the DNA glycosylase-mediated excision of oxidized bases from occluded sites in nucleosomes.The Human Ligase IIIα-XRCC1 Protein Complex Performs DNA Nick Repair after Transient Unwrapping of Nucleosomal DNA.Human OGG1 activity in nucleosomes is facilitated by transient unwrapping of DNA and is influenced by the local histone environment.Probing the activity of NTHL1 orthologs by targeting conserved amino acid residues.
P2860
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P2860
Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
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name
Non-specific DNA binding inter ...... human DNA glycosylase, NEIL1.
@ast
Non-specific DNA binding inter ...... human DNA glycosylase, NEIL1.
@en
type
label
Non-specific DNA binding inter ...... human DNA glycosylase, NEIL1.
@ast
Non-specific DNA binding inter ...... human DNA glycosylase, NEIL1.
@en
prefLabel
Non-specific DNA binding inter ...... human DNA glycosylase, NEIL1.
@ast
Non-specific DNA binding inter ...... human DNA glycosylase, NEIL1.
@en
P2093
P2860
P1433
P1476
Non-specific DNA binding inter ...... e human DNA glycosylase, NEIL1
@en
P2093
David S Pederson
Kheng Newick
Nicholas H Heintz
P2860
P304
P356
10.1016/J.DNAREP.2009.11.005
P577
2009-12-11T00:00:00Z