Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivo
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Host-pathogen interactome mapping for HTLV-1 and -2 retrovirusesBicaudal D1-dependent trafficking of human cytomegalovirus tegument protein pp150 in virus-infected cellsImportin β3 mediates the nuclear import of human ribosomal protein L7 through its interaction with the multifaceted basic clusters of L7Identification of a novel Rev-interacting cellular protein.Presence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein.Roles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replicationNuclear export of proteins and drug resistance in cancerSelective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemiaRegulation of ubiquitin ligase dynamics by the nucleolusCRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis.Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function.Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropismProduction of HIV particles is regulated by altering sub-cellular localization and dynamics of Rev induced by double-strand RNA binding protein.An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production.Influenza virus ribonucleoprotein complexes gain preferential access to cellular export machinery through chromatin targeting.Nullbasic, a potent anti-HIV tat mutant, induces CRM1-dependent disruption of HIV rev traffickingMapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein RevMeasuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluorescence resonance energy transfer.Preclinical evaluation of the novel, orally bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in spontaneous canine cancer: results of a phase I study.Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines.Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma.CRM1 inhibitor S109 suppresses cell proliferation and induces cell cycle arrest in renal cancer cells.Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.Nucleolar aggresomes as counterparts of cytoplasmic aggresomes in proteotoxic stress. Proteasome inhibitors induce nuclear ribonucleoprotein inclusions that accumulate several key factors of neurodegenerative diseases and cancer.The nuclear export factor CRM1 controls juxta-nuclear microtubule-dependent virus transport.A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1.KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant responseProteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability.Puralpha as a cellular co-factor of Rev/RRE-mediated expression of HIV-1 intron-containing mRNA.Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.The mobile FG nucleoporin Nup98 is a cofactor for Crm1-dependent protein export.Is unphosphorylated Rex, as multifunctional protein of HTLV-1, a fully intrinsically disordered protein? An in silico study.Stable assembly of HIV-1 export complexes occurs cotranscriptionally.Fluorescent recovery after photobleaching (FRAP) analysis of nuclear export rates identifies intrinsic features of nucleocytoplasmic transport.The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral StrategiesNucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles
P2860
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P2860
Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivo
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Kinetic and molecular analysis ...... ciation with its cargo in vivo
@ast
Kinetic and molecular analysis ...... ciation with its cargo in vivo
@en
type
label
Kinetic and molecular analysis ...... ciation with its cargo in vivo
@ast
Kinetic and molecular analysis ...... ciation with its cargo in vivo
@en
prefLabel
Kinetic and molecular analysis ...... ciation with its cargo in vivo
@ast
Kinetic and molecular analysis ...... ciation with its cargo in vivo
@en
P2093
P2860
P1476
Kinetic and molecular analysis ...... ciation with its cargo in vivo
@en
P2093
George N Pavlakis
Stephen Lockett
Sylvain V Costes
P2860
P304
P356
10.1128/MCB.25.2.728-739.2005
P407
P577
2005-01-01T00:00:00Z