Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
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Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapyFunctional characterization of human PFTK1 as a cyclin-dependent kinaseA novel, non-apoptotic role for Scythe/BAT3: a functional switch between the pro- and anti-proliferative roles of p21 during the cell cycleMyocardin related transcription factors are required for coordinated cell cycle progression.VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells.WEE1 inhibition alleviates resistance to immune attack of tumor cells undergoing epithelial-mesenchymal transition.1-Oxoeudesm-11(13)-eno-12,8a-lactone induces G2/M arrest and apoptosis of human glioblastoma cells in vitro.Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study.Human GTSE-1 regulates p21(CIP1/WAF1) stability conferring resistance to paclitaxel treatment.Avian reovirus nonstructural protein p17-induced G(2)/M cell cycle arrest and host cellular protein translation shutoff involve activation of p53-dependent pathways.p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker.The heat shock protein 90 inhibitor 17-AAG suppresses growth and induces apoptosis in human cholangiocarcinoma cells.Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathwayCDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cellsCdk2-dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicityLeaf Extracts of Calocedrus formosana (Florin) Induce G2/M Cell Cycle Arrest and Apoptosis in Human Bladder Cancer CellsImpairment of the ubiquitin-proteasome pathway by methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate leads to a potent cytotoxic effect in tumor cells: a novel antiproliferative agent with a potential therapeutic implication.Serine 123 phosphorylation modulates p21 protein stability and activity by suppressing ubiquitin-independent proteasomal degradation.Assembly, activation, and substrate specificity of cyclin D1/Cdk2 complexes.Mitotic p21Cip1/CDKN1A is regulated by cyclin-dependent kinase 1 phosphorylation.Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cellsY14 governs p53 expression and modulates DNA damage sensitivity.Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results.Less understood issues: p21(Cip1) in mitosis and its therapeutic potential.Wip1 contributes to cell homeostasis maintained by the steady-state level of Wtp53.Suppressor of cytokine signaling 1-dependent regulation of the expression and oncogenic functions of p21(CIP1/WAF1) in the liver.Endoplasmic reticulum stress sensitizes cells to DNA damage-induced apoptosis through p53-dependent suppression of p21(CDKN1A).Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway.The cytotoxic activities of 7-isopentenyloxycoumarin on 5637 cells via induction of apoptosis and cell cycle arrest in G2/M stage.p21 overexpression sensitizes osteosarcoma U2OS cells to cisplatin via evoking caspase-3 and Bax/Bcl-2 cascade.p21Waf1/Cip1 deficiency causes multiple mitotic defects in tumor cells.Novel derivative of benzofuran induces cell death mostly by G2/M cell cycle arrest through p53-dependent pathway but partially by inhibition of NF-kappaB.Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.Ceramide-induced G2 arrest in rhabdomyosarcoma (RMS) cells requires p21Cip1/Waf1 induction and is prevented by MDM2 overexpression.Identification of candidate genes for paratuberculosis resistance in the native Italian Garfagnina goat breed.Absolute quantification of multisite phosphorylation by selective reaction monitoring mass spectrometry: determination of inhibitory phosphorylation status of cyclin-dependent kinases.Novel interactions of the von Hippel-Lindau (pVHL) tumor suppressor with the CDKN1 family of cell cycle inhibitors.Withaferin A, a steroidal lactone from Withania somnifera, induces mitotic catastrophe and growth arrest in prostate cancer cellsCardamonin induces ROS-mediated G2/M phase arrest and apoptosis through inhibition of NF-κB pathway in nasopharyngeal carcinoma.The Molecular Mechanisms of Protective Role of Se on the G2/M Phase Arrest of Jejunum Caused by AFB1.
P2860
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P2860
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
@ast
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
@en
type
label
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
@ast
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
@en
prefLabel
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
@ast
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
@en
P2860
P1476
Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
@en
P2093
Bipin C Dash
Wafik S El-Deiry
P2860
P304
P356
10.1128/MCB.25.8.3364-3387.2005
P407
P577
2005-04-01T00:00:00Z