KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter
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Pleiotropic role of HSF1 in neoplastic transformationTumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategiesHeat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an updateThe master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infectionHsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairmentBromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shockAkt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells.TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release.Regulation of the mammalian heat shock factor 1.Celastrol protects ischaemic myocardium through a heat shock response with up-regulation of haeme oxygenase-1.The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters.Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic fluxA semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes.High-throughput screening system for inhibitors of human Heat Shock Factor 2.Heat shock factor 1 induces cancer stem cell phenotype in breast cancer cell linesNMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.Requirement for endogenous heat shock factor 1 in inducible nitric oxide synthase induction in murine microgliaProteotoxic stress of cancer: implication of the heat-shock response in oncogenesis.Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesisHSF1: Guardian of Proteostasis in CancerGlobal cellular response to chemotherapy-induced apoptosis.Transcription regulation of HYPK by Heat Shock Factor 1Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation.Inducible hsp70 in the regulation of cancer cell survival: analysis of chaperone induction, expression and activityHeat shock protein 70 - the next chaperone to target in the treatment of human acute myelogenous leukemia?When Cancer Fights Back: Multiple Myeloma, Proteasome Inhibition, and the Heat-Shock Response.Hsp70-1: upregulation via selective phosphorylation of heat shock factor 1 during coxsackieviral infection and promotion of viral replication via the AU-rich element.Adenomatous polyposis coli mutants dominantly activate Hsf1-dependent cell stress pathways through inhibition of microtubule dynamics.Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737.Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter.HSF1, a versatile factor in tumorogenesis.Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice.Heat Shock Protein 90 Facilitates Latent HIV Reactivation through Maintaining the Function of Positive Transcriptional Elongation Factor b (p-TEFb) under Proteasome Inhibition.Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic ApproachA CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.Loss of AMPK activation promotes the invasion and metastasis of pancreatic cancer through an HSF1-dependent pathwayHSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasisNew inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survivalHDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness.Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin.
P2860
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P2860
KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
KRIBB11 inhibits HSP70 synthes ...... factor b to the hsp70 promoter
@ast
KRIBB11 inhibits HSP70 synthes ...... factor b to the hsp70 promoter
@en
type
label
KRIBB11 inhibits HSP70 synthes ...... factor b to the hsp70 promoter
@ast
KRIBB11 inhibits HSP70 synthes ...... factor b to the hsp70 promoter
@en
prefLabel
KRIBB11 inhibits HSP70 synthes ...... factor b to the hsp70 promoter
@ast
KRIBB11 inhibits HSP70 synthes ...... factor b to the hsp70 promoter
@en
P2093
P2860
P356
P1476
KRIBB11 inhibits HSP70 synthes ...... factor b to the hsp70 promoter
@en
P2093
Byoung-Mog Kwon
Dae-Seop Shin
Dong Cho Han
Jin Soo Lee
Joo Ae Kim
Ki Deok Shin
Young Ju Yoon
Young Min Han
Yu Jin Lee
P2860
P304
P356
10.1074/JBC.M110.179440
P407
P577
2010-11-15T00:00:00Z