Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis - sprookjes - yvandenbroek - TriplyDB

Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis

Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis

http://www.wikidata.org/entity/Q33748201

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Withaferin a alters intermediate filament organization, cell shape and behavior Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo Expression of peptidylarginine deiminase 4 in an alkali injury model of retinal gliosis.Withaferin A induces proteasome inhibition, endoplasmic reticulum stress, the heat shock response and acquisition of thermotolerance.Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis Withaferin A effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis.Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells.Corneal antifibrotic switch identified in genetic and pharmacological deficiency of vimentin Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin.Fluorinated N,N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A Withania somnifera: From prevention to treatment of cancer Physapubescin selectively induces apoptosis in VHL-null renal cell carcinoma cells through down-regulation of HIF-2α and inhibits tumor growth Citrullination of glial intermediate filaments is an early response in retinal injury Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis.Natural product inhibitors of ocular angiogenesis.Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker.The QKI-PLP pathway controls SIRT2 abundance in CNS myelin.Identification of Radial Glia Progenitors in the Developing and Adult Retina of Sharks.A robust model for simultaneously inducing corneal neovascularization and retinal gliosis in the mouse eye.Fisetin enhances behavioral performances and attenuates reactive gliosis and inflammation during aluminum chloride-induced neurotoxicity.Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK.A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers.Assessment of hepatoprotective and nephroprotective potential of withaferin A on bromobenzene-induced injury in Swiss albino mice: possible involvement of mitochondrial dysfunction and inflammation.

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Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis

http://www.wikidata.org/entity/Q33748201

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2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010年の論文

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2010年論文

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Withaferin A targets intermedi ...... in a model of retinal gliosis

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Withaferin A targets intermedi ...... in a model of retinal gliosis

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Adel Hamza

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Beatrice Trucchi

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Chang-Guo Zhan

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Cidambi Srinivasan

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Franca Cambi

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Gregory I Elliott

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Haiyan Zhu

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Kousuke Kasahara

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Masaki Inagaki

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Neviana Dimova

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P2860

The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin

GFAP and its role in Alexander disease

The function of intermediate filaments in cell shape and cytoskeletal integrity

Intermediate-sized filaments of human endothelial cells

Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes.

Phosphorylation sites linked to glial filament disassembly in vitro locate in a non-alpha-helical head domain

Protective role of phosphorylation in turnover of glial fibrillary acidic protein in mice

Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation

Müller cell and neuronal remodeling in retinal detachment and reattachment and their potential consequences for visual recovery: a review and reconsideration of recent data.

14-3-3gamma affects dynamics and integrity of glial filaments by binding to phosphorylated GFAP.

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