Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
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Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugsLocal response of L-type Ca(2+) current to nitric oxide in frog ventricular myocytesSimultaneous measurements of intracellular cAMP and L-type Ca2+ current in single frog ventricular myocytesCyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytesFunctional role of L-type Cav1.3 Ca2+ channels in cardiac pacemaker activityThe VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic HomeostasisMolecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs.Evolution of ventricular myocyte electrophysiology.Transcript scanning reveals novel and extensive splice variations in human l-type voltage-gated calcium channel, Cav1.2 alpha1 subunit.Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse.Atherosclerosis-related molecular alteration of the human CaV1.2 calcium channel alpha1C subunit.Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivationDissecting the functional role of different isoforms of the L-type Ca2+ channel.Alternative splicing modulates diltiazem sensitivity of cardiac and vascular smooth muscle Ca(v)1.2 calcium channels.Smooth muscle-selective alternatively spliced exon generates functional variation in Cav1.2 calcium channels.Fibronectin increases the force production of mouse papillary muscles via α5β1 integrinRegulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein.Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.Functional role of voltage gated Ca(2+) channels in heart automaticity.RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons.Computer modeling of siRNA knockdown effects indicates an essential role of the Ca2+ channel alpha2delta-1 subunit in cardiac excitation-contraction coupling.Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels.Role of action potential configuration and the contribution of C²⁺a and K⁺ currents to isoprenaline-induced changes in canine ventricular cells.Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).Calcium-channel modulators for cardiovascular disease.Understanding alternative splicing of Cav1.2 calcium channels for a new approach towards individualized medicine.Exercise-induced protection against myocardial apoptosis and necrosis: MnSOD, calcium-handling proteins, and calpain.Ca2+ channels in retinal pigment epithelial cells regulate vascular endothelial growth factor secretion rates in health and disease.Similar molecular determinants on Rem mediate two distinct modes of inhibition of CaV1.2 channels.Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissuesWhat can naturally occurring mutations tell us about Ca(v)1.x channel function?Genesis and regulation of the heart automaticity.Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels.Molecular basis for zinc transporter 1 action as an endogenous inhibitor of L-type calcium channels.Loss of β-adrenergic-stimulated phosphorylation of CaV1.2 channels on Ser1700 leads to heart failureRegulation of cardiac excitability by protein kinase C isozymes.The three-dimensional structure of the cardiac L-type voltage-gated calcium channel: comparison with the skeletal muscle form reveals a common architectural motif.L-type Ca2+ channels in heart and brainReview: Cav2.3 R-type Voltage-Gated Ca2+ Channels - Functional Implications in Convulsive and Non-convulsive Seizure Activity.Nifedipine synergizes with calcium in activating the calcium sensing receptor, suppressing the expression of thymidylate synthase and survivin and promoting sensitivity to fluorouracil in human colon carcinoma cells.
P2860
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P2860
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
@ast
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
@en
type
label
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
@ast
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
@en
prefLabel
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
@ast
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
@en
P356
P1476
Pharmacology, structure and function of cardiac L-type Ca(2+) channels.
@en
P2093
Striessnig J
P304
P356
10.1159/000016320
P577
1999-01-01T00:00:00Z