Stat3 activation is required for cellular transformation by v-src.
about
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytesA gain-of-function mutation in STAT6The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent mannerProgesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3SH2B1beta adaptor is a key enhancer of RET tyrosine kinase signalingStructural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motifThe cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cellsErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cellsGRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interactionInteracting regions in Stat3 and c-Jun that participate in cooperative transcriptional activationActivation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoproteinIncreased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinomaSignal transducers and activators of transcription as regulators of growth, apoptosis and breast development.Linear and cooperative signaling: roles for Stat proteins in the regulation of cell survival and apoptosis in the mammary epithelium.Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cellsTyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Nucleic acid-based approaches to STAT inhibitionPlant sterols as anticancer nutrients: evidence for their role in breast cancerEngaged for survival: From cadherin ligation to STAT3 activationActivation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular TransformationDasatinib sensitizes KRAS mutant colorectal tumors to cetuximabInositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicityFER kinase activation of Stat3 is determined by the N-terminal sequenceMet receptor tyrosine kinase: enhanced signaling through adapter proteinsErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinasesThe hunting of the SrcConstitutive activation of STAT transcription factors in acute myelogenous leukemiaFunctional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1aProline-, glutamic acid-, and leucine-rich protein-1 is essential in growth factor regulation of signal transducers and activators of transcription 3 activation.Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solutionSTAT3 as a therapeutic target in head and neck cancerInhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expressionBrain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated TumorigenesisSTAT3 negatively regulates thyroid tumorigenesisSTAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motifScoparone exerts anti-tumor activity against DU145 prostate cancer cells via inhibition of STAT3 activity
P2860
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P2860
Stat3 activation is required for cellular transformation by v-src.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Stat3 activation is required for cellular transformation by v-src.
@ast
Stat3 activation is required for cellular transformation by v-src.
@en
type
label
Stat3 activation is required for cellular transformation by v-src.
@ast
Stat3 activation is required for cellular transformation by v-src.
@en
prefLabel
Stat3 activation is required for cellular transformation by v-src.
@ast
Stat3 activation is required for cellular transformation by v-src.
@en
P2093
P2860
P356
P1476
Stat3 activation is required for cellular transformation by v-src.
@en
P2093
C M Horvath
J E Darnell
J F Bromberg
W W Lathem
P2860
P304
P356
10.1128/MCB.18.5.2553
P407
P577
1998-05-01T00:00:00Z