Stat3 activation is required for cellular transformation by v-src. - sprookjes - yvandenbroek - TriplyDB

Stat3 activation is required for cellular transformation by v-src.

Stat3 activation is required for cellular transformation by v-src.

http://www.wikidata.org/entity/Q33786469

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Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes A gain-of-function mutation in STAT6 The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6 ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3 SH2B1beta adaptor is a key enhancer of RET tyrosine kinase signaling Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3 Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation Activation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoprotein Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development.Linear and cooperative signaling: roles for Stat proteins in the regulation of cell survival and apoptosis in the mammary epithelium.Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Nucleic acid-based approaches to STAT inhibition Plant sterols as anticancer nutrients: evidence for their role in breast cancer Engaged for survival: From cadherin ligation to STAT3 activation Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity FER kinase activation of Stat3 is determined by the N-terminal sequence Met receptor tyrosine kinase: enhanced signaling through adapter proteins ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases The hunting of the Src Constitutive activation of STAT transcription factors in acute myelogenous leukemia Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a Proline-, glutamic acid-, and leucine-rich protein-1 is essential in growth factor regulation of signal transducers and activators of transcription 3 activation.Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution STAT3 as a therapeutic target in head and neck cancer Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis STAT3 negatively regulates thyroid tumorigenesis STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif Scoparone exerts anti-tumor activity against DU145 prostate cancer cells via inhibition of STAT3 activity

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P2860

Stat3 activation is required for cellular transformation by v-src.

http://www.wikidata.org/entity/Q33786469

description

1998 nî lūn-bûn

@nan

1998 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի մայիսին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Stat3 activation is required for cellular transformation by v-src.

@ast

Stat3 activation is required for cellular transformation by v-src.

@en

type

label

Stat3 activation is required for cellular transformation by v-src.

@ast

Stat3 activation is required for cellular transformation by v-src.

@en

prefLabel

Stat3 activation is required for cellular transformation by v-src.

@ast

Stat3 activation is required for cellular transformation by v-src.

@en

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Molecular and Cellular Biology

P1476

Stat3 activation is required for cellular transformation by v-src.

@en

P2093

C M Horvath

http://www.w3.org/2001/XMLSchema#string

D Besser

http://www.w3.org/2001/XMLSchema#string

J E Darnell

http://www.w3.org/2001/XMLSchema#string

J F Bromberg

http://www.w3.org/2001/XMLSchema#string

W W Lathem

http://www.w3.org/2001/XMLSchema#string

P2860

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

Activation and association of Stat3 with Src in v-Src-transformed cell lines

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

Activation of c-Src in cells bearing v-Crk and its suppression by Csk

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2553-2558

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scholarly article

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10.1128/MCB.18.5.2553

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5

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18

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1998-05-01T00:00:00Z

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9566875

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110635

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