Dysregulation of cyclin E gene expression in human cytomegalovirus-infected cells requires viral early gene expression and is associated with changes in the Rb-related protein p130.
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Consensus on the role of human cytomegalovirus in glioblastomaExon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation.Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus.Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits.Inhibition of cyclin-dependent kinase 1 by purines and pyrrolo[2,3-d]pyrimidines does not correlate with antiviral activityInactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.Strategies in subversion: de-regulation of the mammalian cell cycle by viral gene products.SUMO-1 modification of human cytomegalovirus IE1/IE72Tumor control in a model of bone marrow transplantation and acute liver-infiltrating B-cell lymphoma: an unpredicted novel function of cytomegalovirusPUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry.Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32.Infection of a Single Cell Line with Distinct Strains of Human Cytomegalovirus Can Result in Large Variations in Virion Production and Facilitate Efficient Screening of Virus Protein Function.Cell cycle-independent expression of immediate-early gene 3 results in G1 and G2 arrest in murine cytomegalovirus-infected cells.Regulation of the retinoblastoma proteins by the human herpesviruses.Altered subcellular localization of tumor-specific cyclin E isoforms affects cyclin-dependent kinase 2 complex formation and proteasomal regulation.Biologic and immunologic effects of knockout of human cytomegalovirus pp65 nuclear localization signalCyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production.Human cytomegalovirus riding the cell cycle.H2B homology region of major immediate-early protein 1 is essential for murine cytomegalovirus to disrupt nuclear domain 10, but is not important for viral replication in cell culture.Viable human cytomegalovirus recombinant virus with an internal deletion of the IE2 86 gene affects late stages of viral replicationCell cycle arrest by human cytomegalovirus 86-kDa IE2 protein resembles premature senescence.The human cytomegalovirus immediate early 2 protein dissociates cellular DNA synthesis from cyclin-dependent kinase activation.Human cytomegalovirus-encoded viral cyclin-dependent kinase (v-CDK) UL97 phosphorylates and inactivates the retinoblastoma protein-related p107 and p130 proteins.Mechanisms governing maintenance of Cdk1/cyclin B1 kinase activity in cells infected with human cytomegalovirus.PIAS1 enhances SUMO-1 modification and the transactivation activity of the major immediate-early IE2 protein of human cytomegalovirus.Nuclear export of the human cytomegalovirus tegument protein pp65 requires cyclin-dependent kinase activity and the Crm1 exporterMurine cytomegalovirus major immediate-early protein 3 interacts with cellular and viral proteins in viral DNA replication compartments and is important for early gene activation
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P2860
Dysregulation of cyclin E gene expression in human cytomegalovirus-infected cells requires viral early gene expression and is associated with changes in the Rb-related protein p130.
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2000 nî lūn-bûn
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2000年の論文
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2000年論文
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2000年論文
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name
Dysregulation of cyclin E gene ...... n the Rb-related protein p130.
@ast
Dysregulation of cyclin E gene ...... n the Rb-related protein p130.
@en
type
label
Dysregulation of cyclin E gene ...... n the Rb-related protein p130.
@ast
Dysregulation of cyclin E gene ...... n the Rb-related protein p130.
@en
prefLabel
Dysregulation of cyclin E gene ...... n the Rb-related protein p130.
@ast
Dysregulation of cyclin E gene ...... n the Rb-related protein p130.
@en
P2093
P2860
P1433
P1476
Dysregulation of cyclin E gene ...... n the Rb-related protein p130.
@en
P2093
A K McElroy
D H Spector
R S Dwarakanath
P2860
P304
P356
10.1128/JVI.74.9.4192-4206.2000
P577
2000-05-01T00:00:00Z