RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells.
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A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across GenotypesTwo Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405Sphingomyelin activates hepatitis C virus RNA polymerase in a genotype-specific manner.A subclone of HuH-7 with enhanced intracellular hepatitis C virus production and evasion of virus related-cell cycle arrest.Productive homologous and non-homologous recombination of hepatitis C virus in cell culture.Efficient infectious cell culture systems of the hepatitis C virus (HCV) prototype strains HCV-1 and H77.Hepatitis C virus NS3/4A protease inhibits complement activation by cleaving complement component 4SEC14L2 enables pan-genotype HCV replication in cell culture.Production of infectious chimeric hepatitis C virus genotype 2b harboring minimal regions of JFH-1.Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains.Novel cell culture-adapted genotype 2a hepatitis C virus infectious cloneHighly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system.Direct evidence for RNA-RNA interactions at the 3' end of the Hepatitis C virus genome using surface plasmon resonanceCompletion of the Entire Hepatitis C Virus Life Cycle in Vero Cells Derived from Monkey Kidney.Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.Hepatitis C viral protein translation: mechanisms and implications in developing antivirals.Amino Acid Mutations in the NS4A Region of Hepatitis C Virus Contribute to Viral Replication and Infectious Virus ProductionThe conserved 3'X terminal domain of hepatitis C virus genomic RNA forms a two-stem structure that promotes viral RNA dimerization.A twist in the tail: SHAPE mapping of long-range interactions and structural rearrangements of RNA elements involved in HCV replication.Replication and infectivity of a novel genotype 1b hepatitis C virus clone.Three-dimensional structure of the 3'X-tail of hepatitis C virus RNA in monomeric and dimeric states.Evaluating Andrographolide as a Potent Inhibitor of NS3-4A Protease and Its Drug-Resistant Mutants Using In Silico ApproachesRegulation of CCN1 via the 3'-untranslated region.An unexpected RNA distal interaction mode found in an essential region of the hepatitis C virus genome.
P2860
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P2860
RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
RNA polymerase activity and sp ...... replication in cultured cells.
@ast
RNA polymerase activity and sp ...... replication in cultured cells.
@en
type
label
RNA polymerase activity and sp ...... replication in cultured cells.
@ast
RNA polymerase activity and sp ...... replication in cultured cells.
@en
prefLabel
RNA polymerase activity and sp ...... replication in cultured cells.
@ast
RNA polymerase activity and sp ...... replication in cultured cells.
@en
P2093
P2860
P1433
P1476
RNA polymerase activity and sp ...... replication in cultured cells.
@en
P2093
Asako Murayama
Daisuke Akazawa
Leiyun Weng
Masashi Mizokami
Takaji Wakita
Takanobu Kato
Tetsuro Suzuki
Tetsuya Toyoda
Tomoko Date
Yasuhito Tanaka
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000885
P50
P577
2010-04-29T00:00:00Z