RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells. - sprookjes - yvandenbroek - TriplyDB

RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells.

RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells.

http://www.wikidata.org/entity/Q33818878

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A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405 Sphingomyelin activates hepatitis C virus RNA polymerase in a genotype-specific manner.A subclone of HuH-7 with enhanced intracellular hepatitis C virus production and evasion of virus related-cell cycle arrest.Productive homologous and non-homologous recombination of hepatitis C virus in cell culture.Efficient infectious cell culture systems of the hepatitis C virus (HCV) prototype strains HCV-1 and H77.Hepatitis C virus NS3/4A protease inhibits complement activation by cleaving complement component 4 SEC14L2 enables pan-genotype HCV replication in cell culture.Production of infectious chimeric hepatitis C virus genotype 2b harboring minimal regions of JFH-1.Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains.Novel cell culture-adapted genotype 2a hepatitis C virus infectious clone Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system.Direct evidence for RNA-RNA interactions at the 3' end of the Hepatitis C virus genome using surface plasmon resonance Completion of the Entire Hepatitis C Virus Life Cycle in Vero Cells Derived from Monkey Kidney.Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.Hepatitis C viral protein translation: mechanisms and implications in developing antivirals.Amino Acid Mutations in the NS4A Region of Hepatitis C Virus Contribute to Viral Replication and Infectious Virus Production The conserved 3'X terminal domain of hepatitis C virus genomic RNA forms a two-stem structure that promotes viral RNA dimerization.A twist in the tail: SHAPE mapping of long-range interactions and structural rearrangements of RNA elements involved in HCV replication.Replication and infectivity of a novel genotype 1b hepatitis C virus clone.Three-dimensional structure of the 3'X-tail of hepatitis C virus RNA in monomeric and dimeric states.Evaluating Andrographolide as a Potent Inhibitor of NS3-4A Protease and Its Drug-Resistant Mutants Using In Silico Approaches Regulation of CCN1 via the 3'-untranslated region.An unexpected RNA distal interaction mode found in an essential region of the hepatitis C virus genome.

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P2860

RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells.

http://www.wikidata.org/entity/Q33818878

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

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name

RNA polymerase activity and sp ...... replication in cultured cells.

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RNA polymerase activity and sp ...... replication in cultured cells.

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RNA polymerase activity and sp ...... replication in cultured cells.

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JOURNAL.PPAT.1000885

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RNA polymerase activity and sp ...... replication in cultured cells.

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Asako Murayama

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Daisuke Akazawa

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Leiyun Weng

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Masashi Mizokami

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Takaji Wakita

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Takanobu Kato

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Tetsuro Suzuki

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Tetsuya Toyoda

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Tomoko Date

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Yasuhito Tanaka

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P2860

Mfold web server for nucleic acid folding and hybridization prediction

A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication

Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase.

De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus

Robust hepatitis C virus infection in vitro.

Mutagenesis analysis of the rGTP-specific binding site of hepatitis C virus RNA-dependent RNA polymerase

Detection of anti-hepatitis C virus effects of interferon and ribavirin by a sensitive replicon system.

Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

hnRNP C and polypyrimidine tract-binding protein specifically interact with the pyrimidine-rich region within the 3'NTR of the HCV RNA genome

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e1000885

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