about
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiologyComprehensive assessment of human pharmacokinetic prediction based on in vivo animal pharmacokinetic data, part 2: clearance.Mechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro Data.The Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of Imipramine.Physiologically based pharmacokinetic modeling framework for quantitative prediction of an herb-drug interaction.Predicting effects on oxaliplatin clearance: in vitro, kinetic and clinical studies of calcium- and magnesium-mediated oxaliplatin degradationSandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity.In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability.An evaluation of the latest in vitro tools for drug metabolism studies.Clinically Relevant Concentrations of Anticancer Drugs: A Guide for Nonclinical Studies.Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels.Determination of Human Hepatocyte Intrinsic Clearance for Slowly Metabolized Compounds: Comparison of a Primary Hepatocyte/Stromal Cell Co-culture with Plated Primary Hepatocytes and HepaRG.Verapamil hepatic clearance in four preclinical rat models: towards activity-based scaling.Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.Metabolism and clinical pharmacokinetics of 2-methyl-n-(2'-(pyrrolidinyl-1-ylsulfonyl)-n-[1,1'-biphenyl]-4-yl)propran-1-amine: insights into monoamine oxidase- and CYP-mediated disposition by integration of in vitro ADME tools.Drug Distribution Part 2. Predicting Volume of Distribution from Plasma Protein Binding and Membrane Partitioning.
P2860
Q26852097-944CA3DB-C45D-45F9-ABD7-DAE0C920F1FCQ30593578-C9498ECB-EC32-404B-B84E-112C82B4A083Q31054926-05BA6F24-A15B-441B-82D5-5A36BA138C40Q31116232-64F85929-BB10-479D-A4A5-7A20A19A69BDQ33702513-B744836D-7791-4156-A72B-C59945509A4EQ33826355-CE45B639-8B31-4BF4-9794-ECB90213DDD9Q34330504-33569FFB-789B-4F0E-98D9-4CED698BBB84Q38107523-1A8635FC-5350-4EAB-8BAF-77885D8491ABQ38160881-FA59C629-37C7-4C98-AFAC-430151483AE2Q38863833-7A6AF4F7-4773-44BB-9CA6-57F5689F3920Q39666574-22E4E9F9-91D5-4740-B427-26F44B4A07EAQ39984138-E4CA3F0F-44B0-4E5E-A3F9-6DDD1862E26CQ40018596-E0B66A86-23AE-419F-B8D5-1B123A49A09BQ40950708-80AFDA09-2A1C-4A4B-B30F-3556209B24B7Q41432197-56112144-1BD7-43D4-8729-9CC6B1845440Q45900576-36C4E49F-C0BE-48FD-811D-805A43D9E7CEQ48158248-37285CCA-EF1F-4E82-8863-7DE334A4E018
P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Predicting clearance in humans from in vitro data.
@ast
Predicting clearance in humans from in vitro data.
@en
type
label
Predicting clearance in humans from in vitro data.
@ast
Predicting clearance in humans from in vitro data.
@en
prefLabel
Predicting clearance in humans from in vitro data.
@ast
Predicting clearance in humans from in vitro data.
@en
P1476
Predicting clearance in humans from in vitro data.
@en
P2093
R Scott Obach
P304
P356
10.2174/156802611794480873
P577
2011-01-01T00:00:00Z