Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation.
about
Blockade of VEGFR1 and 2 suppresses pathological angiogenesis and vascular leakage in the eyeA first-in-human phase I dose-escalation, pharmacokinetic, and pharmacodynamic evaluation of intravenous LY2090314, a glycogen synthase kinase 3 inhibitor, administered in combination with pemetrexed and carboplatin.VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity.Platelet-derived growth factor signaling in the lung. From lung development and disease to clinical studies.Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts.An ANOCEF genomic and transcriptomic microarray study of the response to irinotecan and bevacizumab in recurrent glioblastomas.A Review of Anti-Angiogenic Targets for Monoclonal Antibody Cancer TherapyIntegrative analysis of miRNA and mRNA paired expression profiling of primary fibroblast derived from diabetic foot ulcers reveals multiple impaired cellular functions.Moderate GSK-3β inhibition improves neovascular architecture, reduces vascular leakage, and reduces retinal hypoxia in a model of ischemic retinopathy.Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation.Dkk-1 promotes angiogenic responses and cartilage matrix proteinase secretion in synovial fibroblasts from osteoarthritic joints.
P2860
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P2860
Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Platelet-derived growth factor ...... kinase-3beta phosphorylation.
@ast
Platelet-derived growth factor ...... kinase-3beta phosphorylation.
@en
type
label
Platelet-derived growth factor ...... kinase-3beta phosphorylation.
@ast
Platelet-derived growth factor ...... kinase-3beta phosphorylation.
@en
prefLabel
Platelet-derived growth factor ...... kinase-3beta phosphorylation.
@ast
Platelet-derived growth factor ...... kinase-3beta phosphorylation.
@en
P2093
P2860
P356
P1476
Platelet-derived growth factor ...... kinase-3beta phosphorylation.
@en
P2093
Anil Kumar
Arvydas Maminishkis
Chunsik Lee
Harald F Langer
Lianchun Wang
Lijin Dong
Linda Y Zhu
Pachiappan Arjunan
Peter Colosi
P2860
P304
15500-15510
P356
10.1074/JBC.M110.113787
P407
P577
2010-03-15T00:00:00Z