Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli - sprookjes - yvandenbroek - TriplyDB

Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

http://www.wikidata.org/entity/Q33841885

about

The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner.Cell-autonomous requirement for beta1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice.Conditional knockout of fibronectin abrogates mouse mammary gland lobuloalveolar differentiation.Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging.Control of mammary myoepithelial cell contractile function by α3β1 integrin signalling Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate.Connective Tissue Growth Factor (CTGF/CCN2) enhances lactogenic differentiation of mammary epithelial cells via integrin-mediated cell adhesion Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer Cellular microenvironment influences the ability of mammary epithelia to undergo cell cycle.Comparative 2D-DIGE proteomic analysis of bovine mammary epithelial cells during lactation reveals protein signatures for lactation persistency and milk yield Interstitial guidance of cancer invasion.Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats.Cell-matrix interactions in mammary gland development and breast cancer Dystroglycan controls signaling of multiple hormones through modulation of STAT5 activity.When Cre-mediated recombination in mice does not result in protein loss.The mammary cellular hierarchy and breast cancer.Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression Integrins regulate epithelial cell differentiation by modulating Notch activity.Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium.The C terminus of talin links integrins to cell cycle progression.Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function.β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer.Microenvironmental control of the breast cancer cell cycle.Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype.Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model CD151 represses mammary gland development by maintaining the niches of progenitor cells.Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression.Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.Beta 1 integrin predicts survival in breast cancer: a clinicopathological and immunohistochemical study.Relationship between histology, development and tumorigenesis of mammary gland in female rat.Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity The extracellular matrix as an adhesion checkpoint for mammary epithelial function.PIASy represses CCAAT/enhancer-binding protein delta (C/EBPdelta) transcriptional activity by sequestering C/EBPdelta to the nuclear periphery.beta1 integrin as a molecular therapeutic target.β1 integrin is a crucial regulator of pancreatic β-cell expansion.

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P2860

Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

http://www.wikidata.org/entity/Q33841885

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Beta1 integrins regulate mamma ...... e integrity of mammary alveoli

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Beta1 integrins regulate mamma ...... e integrity of mammary alveoli

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SJ.EMBOJ.7600674

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The EMBO Journal

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Beta1 integrins regulate mamma ...... e integrity of mammary alveoli

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Charles H Streuli

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Francisca Maurer

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Franziska Schatzmann

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Gunther Schuetz

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Matthew J Naylor

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Na Li

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Nancy E Hynes

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Tim Wintermantel

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Ulrich Mueller

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Yu Zhang

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P2860

Integrins: bidirectional, allosteric signaling machines

Integrin signaling

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine

Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis

Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement.

Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells.

Extracellular matrix remodelling and cellular differentiation.

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1942-1953

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10.1038/SJ.EMBOJ.7600674

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11

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24

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2005-05-12T00:00:00Z

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7852447

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15889143

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1142608

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