BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity.
about
BAG3: a new player in the heart failure paradigmBIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cellsThe specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability.Thimerosal-induced apoptosis in mouse C2C12 myoblast cells occurs through suppression of the PI3K/Akt/survivin pathwayThe novel αB-crystallin (CRYAB) mutation p.D109G causes restrictive cardiomyopathy.Small heat shock proteins in redox metabolism: implications for cardiovascular diseases.Novel roles for α-crystallins in retinal function and disease.BAG3-dependent noncanonical autophagy induced by proteasome inhibition in HepG2 cellsNFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation.Large potentials of small heat shock proteins.Genetic cardiomyopathies. Lessons learned from humans, mice, and zebrafish.Genetics in dilated cardiomyopathy.Contribution of small heat shock proteins to muscle development and function.Barcoding heat shock proteins to human diseases: looking beyond the heat shock responseAn interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8.The growing world of small heat shock proteins: from structure to functions.Proteostasis in cardiac health and disease.Aggregate-prone R120GCRYAB triggers multifaceted modifications of the thioredoxin system.Chaperones: needed for both the good times and the bad times.BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins.The Potential Functions of Small Heat Shock Proteins in the Uterine Musculature during Pregnancy.The role of heat shock proteins and co-chaperones in heart failure.HSPB8 and the Cochaperone BAG3 Are Highly Expressed During the Synthetic Phase of Rat Myometrium Programming During Pregnancy.The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease.Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytesZebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency
P2860
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P2860
BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
BAG3 directly interacts with m ...... its aggregation and toxicity.
@ast
BAG3 directly interacts with m ...... its aggregation and toxicity.
@en
type
label
BAG3 directly interacts with m ...... its aggregation and toxicity.
@ast
BAG3 directly interacts with m ...... its aggregation and toxicity.
@en
prefLabel
BAG3 directly interacts with m ...... its aggregation and toxicity.
@ast
BAG3 directly interacts with m ...... its aggregation and toxicity.
@en
P2093
P2860
P1433
P1476
BAG3 directly interacts with m ...... its aggregation and toxicity.
@en
P2093
Akinori Hishiya
Mortada Najem Salman
Shinichi Takayama
P2860
P304
P356
10.1371/JOURNAL.PONE.0016828
P407
P577
2011-03-15T00:00:00Z