A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets
about
Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase CRAP2B: a RAS-related GTP-binding protein from plateletsFunctional relationship between cyclic AMP-dependent protein phosphorylation and platelet inhibitionReversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycleBromodomain protein Brd4 binds to GTPase-activating SPA-1, modulating its activity and subcellular localizationIdentification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteinsAssociation of the low molecular weight GTP-binding protein rap2B with the cytoskeleton during platelet aggregationcDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranescAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factorAssociation of the GTP-binding protein Rab3A with bovine adrenal chromaffin granules.GTP-binding proteins and regulated exocytosis.Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341.Glycoprotein IIb-IIIa and the translocation of Rap2B to the platelet cytoskeleton.Expression of the gene for a small GTP binding protein in transgenic tobacco elevates endogenous cytokinin levels, abnormally induces salicylic acid in response to wounding, and increases resistance to tobacco mosaic virus infectionStructure, functional regulation and signaling properties of Rap2B.Epinephrine suppresses rap1B.GAP-activated GTPase activity in human platelets.Role of rap1B and p21ras GTPase-activating protein in the regulation of phospholipase C-gamma 1 in human plateletsPhosphorylation of a Ras-related GTP-binding protein, Rap-1b, by a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase Gr.Thrombolamban, the 22-kDa platelet substrate of cyclic AMP-dependent protein kinase, is immunologically homologous with the Ras family of GTP-binding proteins.The signal transduction induced by thrombin in human platelets.Novel roles of cAMP/cGMP-dependent signaling in platelets.The control of blood platelets by cAMP signalling.Platelet activation and inhibition. Novel signal transduction mechanisms.Quantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: lack of Rap 1 activation in variant cells.Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteinsProtein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytesActivation of brain B-Raf protein kinase by Rap1B small GTP-binding protein.The novel cyclic dinucleotide 3'-5' cyclic diguanylic acid binds to p21ras and enhances DNA synthesis but not cell replication in the Molt 4 cell line.Correlated expression of the 97 kDa sarcoendoplasmic reticulum Ca(2+)-ATPase and Rap1B in platelets and various cell lines.In search of a function for the Ras-like GTPase Rap1.Redistribution of ADP-ribosylation factor during stimulation of permeabilized cells with GTP analogues.GTP analogues cause preferential translocation of an 18 kDa cytosolic G-protein to the membrane fraction in the ZR-75-1 human breast-cancer cell line.Rapid Ca2+-mediated activation of Rap1 in human plateletsRap1b is critical for glycoprotein VI-mediated but not ADP receptor-mediated alpha2beta1 activation.The tumor suppressor RASSF1A is a novel effector of small G protein Rap1A.The Small GTPase Rap1b: A Bidirectional Regulator of Platelet Adhesion Receptors.RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation.Distribution of polypeptides binding guanosine 5'-[gamma-[35S]thio]triphosphate and anti-(ras protein) antibodies in liver subcellular fractions. Evidence for endosome-specific components.Evidence for a role of rap1 protein in the regulation of human platelet Ca2+ fluxes
P2860
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P2860
A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets
description
1989 nî lūn-bûn
@nan
1989 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
A ras-related protein is phosp ...... cAMP levels in human platelets
@ast
A ras-related protein is phosp ...... cAMP levels in human platelets
@en
type
label
A ras-related protein is phosp ...... cAMP levels in human platelets
@ast
A ras-related protein is phosp ...... cAMP levels in human platelets
@en
prefLabel
A ras-related protein is phosp ...... cAMP levels in human platelets
@ast
A ras-related protein is phosp ...... cAMP levels in human platelets
@en
P2093
P2860
P356
P1476
A ras-related protein is phosp ...... cAMP levels in human platelets
@en
P2093
Lapetina EG
Molina y Vedia L
P2860
P304
P356
10.1073/PNAS.86.9.3131
P407
P577
1989-05-01T00:00:00Z