Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae
about
Replicative and chronological aging in Saccharomyces cerevisiae.Mitotic exit and separation of mother and daughter cellsPreferential retrotransposition in aging yeast mother cells is correlated with increased genome instability.Detectable clonal mosaicism from birth to old age and its relationship to cancerGrowth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocationsThe Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Grabbing the genome by the NADsA sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cellNucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast agingRole of SAGA in the asymmetric segregation of DNA circles during yeast ageing.A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespanCombining magnetic sorting of mother cells and fluctuation tests to analyze genome instability during mitotic cell aging in Saccharomyces cerevisiae.Retrotransposition is associated with genome instability during chronological aging.Organelle segregation during mitosis: lessons from asymmetrically dividing cells.Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast geneticsNatural genetic variation in yeast longevity.Epigenetic modification of the repair donor regulates targeted gene correction.rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants.Gamete formation resets the aging clock in yeast.Identification of Genes in Saccharomyces cerevisiae that Are Haploinsufficient for Overcoming Amino Acid Starvation.Running on empty: does mitochondrial DNA mutation limit replicative lifespan in yeast?: Mutations that increase the division rate of cells lacking mitochondrial DNA also extend replicative lifespan in Saccharomyces cerevisiae.Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.Mitochondria in ageing: there is metabolism beyond the ROS.Budding yeast as a model organism to study the effects of age.Quasi-programmed aging of budding yeast: a trade-off between programmed processes of cell proliferation, differentiation, stress response, survival and death defines yeast lifespan.End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging.Somatic recombination in adult tissues: What is there to learn?Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae.An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast.The cell biology of open and closed mitosis.Multigenerational silencing dynamics control cell aging.A growing role for hypertrophy in senescence.Absence of Non-histone Protein Complexes at Natural Chromosomal Pause Sites Results in Reduced Replication Pausing in Aging Yeast Cells.Aggregation of the Whi3 protein, not loss of heterochromatin, causes sterility in old yeast cells.Heat stress promotes longevity in budding yeast by relaxing the confinement of age-promoting factors in the mother cell.Impaired cohesion and homologous recombination during replicative aging in budding yeast.Osh6 overexpression extends the lifespan of yeast by increasing vacuole fusion.
P2860
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P2860
Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Replicative age induces mitoti ...... er of Saccharomyces cerevisiae
@ast
Replicative age induces mitoti ...... er of Saccharomyces cerevisiae
@en
type
label
Replicative age induces mitoti ...... er of Saccharomyces cerevisiae
@ast
Replicative age induces mitoti ...... er of Saccharomyces cerevisiae
@en
prefLabel
Replicative age induces mitoti ...... er of Saccharomyces cerevisiae
@ast
Replicative age induces mitoti ...... er of Saccharomyces cerevisiae
@en
P2093
P2860
P1433
P1476
Replicative age induces mitoti ...... er of Saccharomyces cerevisiae
@en
P2093
Christina K Leverich
Daniel E Gottschling
Derek L Lindstrom
Kiersten A Henderson
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002015
P577
2011-03-17T00:00:00Z