Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
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Spontaneous generation of prion infectivity in fatal familial insomnia knockin miceA novel human disease with abnormal prion protein sensitive to proteaseQuantum dots and prion proteins: is this a new challenge for neurodegenerative diseases imaging?The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyTransmissibility of atypical scrapie in ovine transgenic mice: major effects of host prion protein expression and donor prion genotypePrPC directly interacts with proteins involved in signaling pathwaysEarly Vertebrate Evolution of the Host Restriction Factor TetherinCounteraction of the multifunctional restriction factor tetherinReduced translocation of nascent prion protein during ER stress contributes to neurodegeneration.Utilizing NMR and EPR spectroscopy to probe the role of copper in prion diseases.Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration.Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway.Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegenerationMolecular distinction between pathogenic and infectious properties of the prion protein.Selective processing and metabolism of disease-causing mutant prion proteins.Unexpected tolerance of alpha-cleavage of the prion protein to sequence variationsSignal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein.Cell type-specific neuroprotective activity of untranslocated prion protein.A novel PrP partner HS-1 associated protein X-1 (HAX-1) protected the cultured cells against the challenge of H₂O₂.Redox control of prion and disease pathogenesis.Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesisMetabolism of minor isoforms of prion proteins: Cytosolic prion protein and transmembrane prion proteinVariably protease-sensitive prionopathy: a new sporadic disease of the prion protein.Pathogenesis of prion diseases: a progress report.Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel.Propagation of RML prions in mice expressing PrP devoid of GPI anchor leads to formation of a novel, stable prion strainCompartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo.Review: contribution of transgenic models to understanding human prion disease.Cell-specific metabolism and pathogenesis of transmembrane prion protein.What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired?Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion diseaseTransmission characteristics of variably protease-sensitive prionopathy.High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrPSc in vivo.Conformational control through translocational regulation: a new view of secretory and membrane protein folding.Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgeneInherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein.The transmissible spongiform encephalopathies: pathogenic mechanisms and strategies for therapeutic intervention.Prion protein biosynthesis and its emerging role in neurodegeneration.Recent developments in the pathogenesis, diagnosis, and therapy of prion diseases.(Ctm)PrP and ER stress: a neurotoxic mechanism of some special PrP mutants.
P2860
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P2860
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
@ast
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
@en
type
label
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
@ast
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
@en
prefLabel
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
@ast
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
@en
P2093
P2860
P50
P356
P1433
P1476
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
@en
P2093
P2860
P2888
P304
P356
10.1038/45574
P407
P577
1999-12-01T00:00:00Z
P5875
P6179
1014361919