TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus
about
Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationThe germinal center antibody response in health and diseaseIntracellular nucleic acid sensors and autoimmunityCytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNATLRs and interferons: a central paradigm in autoimmunityToll-like receptors in the pathogenesis of autoimmune diseases: recent and emerging translational developmentsSexual dimorphism in autoimmunityNucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and AutoinflammationThe receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunityNucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responsesEstrogen receptor alpha modulates Toll-like receptor signaling in murine lupusHLA-DR3 restricted T cell epitope mimicry in induction of autoimmune response to lupus-associated antigen SmDTargeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9Pathways leading to an immunological disease: systemic lupus erythematosus.Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus.Leaky Gut As a Danger Signal for Autoimmune DiseasesRNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.Spontaneous activation of RNA-sensing pathways in autoimmune disease.Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient miceAltered B cell signalling in autoimmunity.Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis.Humanized TLR7/8 expression drives proliferative multisystemic histiocytosis in C57BL/6 mice.B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9.Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damageToll-like receptors in systemic lupus erythematosus: potential for personalized treatment.Requirements for innate immune pathways in environmentally induced autoimmunity.Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulinTLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNSTLR7- and TLR9-responsive human B cells share phenotypic and genetic characteristics.Using Poly I:C as an adjuvant does not induce or exacerbate models of systemic lupus erythematosus.Cytokine disturbances in systemic lupus erythematosus.B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice.A tolerogenic role for Toll-like receptor 9 is revealed by B-cell interaction with DNA complexes expressed on apoptotic cellsToll-like receptors: potential targets for lupus treatmentUnbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production.Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity.BANK1 Regulates IgG Production in a Lupus Model by Controlling TLR7-Dependent STAT1 Activation.
P2860
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P2860
TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
TLR9 regulates TLR7- and MyD88 ...... ase in a murine model of lupus
@ast
TLR9 regulates TLR7- and MyD88 ...... ase in a murine model of lupus
@en
type
label
TLR9 regulates TLR7- and MyD88 ...... ase in a murine model of lupus
@ast
TLR9 regulates TLR7- and MyD88 ...... ase in a murine model of lupus
@en
prefLabel
TLR9 regulates TLR7- and MyD88 ...... ase in a murine model of lupus
@ast
TLR9 regulates TLR7- and MyD88 ...... ase in a murine model of lupus
@en
P2093
P2860
P356
P1476
TLR9 regulates TLR7- and MyD88 ...... ase in a murine model of lupus
@en
P2093
Daniel Kim
Jonathan Shupe
Keith Elkon
Kevin M Nickerson
Mark J Shlomchik
Michael Kashgarian
Sean R Christensen
P2860
P304
P356
10.4049/JIMMUNOL.0902592
P407
P577
2010-01-20T00:00:00Z