The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
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Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.LDL receptor-related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cellsGlucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferationRegulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpADysregulation of integrin-linked kinase (ILK) signaling in colonic polyposisCyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanismCyclins: roles in mitogenic signaling and oncogenic transformationTransfection of K-rasAsp12 cDNA markedly elevates IL-1beta- and lipopolysaccharide-mediated inducible nitric oxide synthase expression in rat intestinal epithelial cellsTranscriptional regulation of the promoter of the rat frizzled related protein gene by CREBIntegrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesisReduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytesIntegrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylationJunctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity.Allosteric modulation of beta1 integrin function induces lung tissue repairInositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as potential target.Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancerIntegration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.Effects of gastrin 17 on beta-catenin/Tcf-4 pathway in Colo320WT colon cancer cellsA novel role for integrin-linked kinase in epithelial sheet morphogenesisActivating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes.Cooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor developmentIKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.An extracellular signal-regulated kinase 1- and 2-dependent program of chromatin trafficking of c-Fos and Fra-1 is required for cyclin D1 expression during cell cycle reentry.ILKAP regulates ILK signaling and inhibits anchorage-independent growth.Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer.Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexesCalcyclin-binding protein/Siah-1-interacting protein as a regulator of transcriptional responses in brain cells.A Tale of Two Signals: AR and WNT in Development and Tumorigenesis of Prostate and Mammary Gland.An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2.Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria.Requirement of epithelial integrin-linked kinase for facilitation of Citrobacter rodentium-induced colitis.Cyclin D1 governs adhesion and motility of macrophages.Neuroprotective actions of ghrelin and growth hormone secretagogues.PI3K/Akt and apoptosis: size matters.The elements of human cyclin D1 promoter and regulation involved.Winding through the WNT pathway during cellular development and demiseThe ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell densityThe SPARC-related factor SMOC-2 promotes growth factor-induced cyclin D1 expression and DNA synthesis via integrin-linked kinase.Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation.Pocket protein function in melanocyte homeostasis and neoplasia.
P2860
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P2860
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The integrin-linked kinase reg ...... ng protein-dependent pathways.
@ast
The integrin-linked kinase reg ...... ng protein-dependent pathways.
@en
type
label
The integrin-linked kinase reg ...... ng protein-dependent pathways.
@ast
The integrin-linked kinase reg ...... ng protein-dependent pathways.
@en
prefLabel
The integrin-linked kinase reg ...... ng protein-dependent pathways.
@ast
The integrin-linked kinase reg ...... ng protein-dependent pathways.
@en
P2093
P356
P1476
The integrin-linked kinase reg ...... ing protein-dependent pathways
@en
P2093
Albanese C
Amanatullah DF
Augenlicht LH
Bouzahzah B
Donehower LA
P304
32649-32657
P356
10.1074/JBC.M000643200
P407
P50
P577
2000-10-01T00:00:00Z