Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo.
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IMMUNOLOGY OF TUBERCULOSISTuberculosis vaccines and prevention of infectionTB vaccines; promoting rapid and durable protection in the lungImmunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during TreatmentPathogen-related differences in the abundance of presented antigen are reflected in CD4+ T cell dynamic behavior and effector function in the lung.The HyVac4 subunit vaccine efficiently boosts BCG-primed anti-mycobacterial protective immunityNovel vaccination strategies against tuberculosis.CD4+ T cells contain early extrapulmonary tuberculosis (TB) dissemination and rapid TB progression and sustain multieffector functions of CD8+ T and CD3- lymphocytes: mechanisms of CD4+ T cell immunity.Cell-to-cell transfer of M. tuberculosis antigens optimizes CD4 T cell primingWhat do we really know about how CD4 T cells control Mycobacterium tuberculosis?Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge.Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development.Beyond macrophages: the diversity of mononuclear cells in tuberculosis.Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ΔureC::hly vaccine's superior protection against tuberculosisOrchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.T Cell Activation and Proinflammatory Cytokine Production in Clinically Cured Tuberculosis Are Time-Dependent and Accompanied by Upregulation of IL-10.B cells enhance antigen-specific CD4 T cell priming and prevent bacteria dissemination following Chlamydia muridarum genital tract infection.Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosisMouse model of tuberculosisCharacterization of effector and memory T cell subsets in the immune response to bovine tuberculosis in cattle.ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis.Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells.Impaired fitness of Mycobacterium africanum despite secretion of ESAT-6A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during TuberculosisSTIM1 controls T cell-mediated immune regulation and inflammation in chronic infection.Cellular and humoral mechanisms involved in the control of tuberculosisCD4+ T cell-dependent IFN-γ production by CD8+ effector T cells in Mycobacterium tuberculosis infectionControl of T cell antigen reactivity via programmed TCR downregulation.CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease.Maintenance of peripheral T cell responses during Mycobacterium tuberculosis infection.Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing.Tuberculosis vaccine with high predicted population coverage and compatibility with modern diagnosticsSequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognitionCD4+ T Cells: guardians of the phagosome.Revisiting the role of the granuloma in tuberculosis.Protection versus pathology in tuberculosis: recent insights.Cytokines in the balance of protection and pathology during mycobacterial infections.The onset of adaptive immunity in the mouse model of tuberculosis and the factors that compromise its expression.Fibronectin binding protein and Ca2+ play an access key role to mediate pathogenesis in Mycobacterium tuberculosis: An overview.Type I, II, and III Interferons: Regulating Immunity to Mycobacterium tuberculosis Infection.
P2860
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P2860
Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Suboptimal activation of antig ...... ce of M. tuberculosis in vivo.
@ast
Suboptimal activation of antig ...... ce of M. tuberculosis in vivo.
@en
type
label
Suboptimal activation of antig ...... ce of M. tuberculosis in vivo.
@ast
Suboptimal activation of antig ...... ce of M. tuberculosis in vivo.
@en
prefLabel
Suboptimal activation of antig ...... ce of M. tuberculosis in vivo.
@ast
Suboptimal activation of antig ...... ce of M. tuberculosis in vivo.
@en
P2093
P2860
P1433
P1476
Suboptimal activation of antig ...... ce of M. tuberculosis in vivo.
@en
P2093
Andrea J Wolf
Niaz Banaei
Tyler D Bold
P2860
P304
P356
10.1371/JOURNAL.PPAT.1002063
P50
P577
2011-05-26T00:00:00Z