A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism
about
Mediator-dependent nuclear receptor functionThe Mediator complex and transcription regulationA cardiac microRNA governs systemic energy homeostasis by regulation of MED13Transcriptional coregulators: fine-tuning metabolism.Coactivators in PPAR-Regulated Gene ExpressionAbsence of RIP140 reveals a pathway regulating glut4-dependent glucose uptake in oxidative skeletal muscle through UCP1-mediated activation of AMPK.Mediator complex dependent regulation of cardiac development and disease.Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.Minireview: estrogen receptor-initiated mechanisms causal to mammalian reproductive behaviors.MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liverLeucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous systemMuscle as a "mediator" of systemic metabolismLethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.Maintaining ancient organelles: mitochondrial biogenesis and maturation.Coactivator MED1 ablation in keratinocytes results in hair-cycling defects and epidermal alterations.Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4.Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid compositionA MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism.General molecular biology and architecture of nuclear receptors.The Mediator Complex and Lipid Metabolism.Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat dietThe Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase.Regulation of metabolism by the Mediator complex.Leanness and heightened nonresting energy expenditure: role of skeletal muscle activity thermogenesis.Essential role of TEA domain transcription factors in the negative regulation of the MYH 7 gene by thyroid hormone and its receptors.Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesisTranscriptional analysis of brown adipose tissue in leptin-deficient mice lacking inducible nitric oxide synthase: evidence of the role of Med1 in energy balance.Exploring the emerging complexity in transcriptional regulation of energy homeostasis.Mediator 1 Is Atherosclerosis Protective by Regulating Macrophage Polarization.Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.MicroRNAs 33, 122, and 208: a potential novel targets in the treatment of obesity, diabetes, and heart-related diseases.Coregulator-mediated control of skeletal muscle plasticity - A mini-reviewAdipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance.Molecular profiling of dilated cardiomyopathy that progresses to heart failure.Control of Muscle Metabolism by the Mediator Complex.
P2860
Q26995848-48236CBE-D529-4252-AFA8-F17B18EEB11DQ28299679-934C2CC9-1106-4A8E-A339-3B651BCD9164Q28505950-ACE92771-4908-420F-ADE0-5EBC4AA2E816Q33838571-9C78D80A-5365-443A-91CA-93170189F3C9Q34089711-823223A8-BCA6-4A60-B900-6ED6201F08E5Q34184597-32EDA96C-D55E-4551-B4BE-D16F98046A6FQ34348002-EF2A9736-D708-48A7-B316-01B877893CCDQ34608360-D3AA0BF5-1D1D-4E20-B0E8-A3647C15CE99Q34697041-2FAE3F74-BF01-4D38-BBC9-E3893C247294Q34881000-1463DA94-F75A-4F5B-8EDA-844AC8D2BC07Q35193150-1265602A-CE01-4378-945D-672DA6FDDF52Q35429223-8DF72469-2D93-4B9A-86B5-B5F69472B9FAQ35621184-561F121C-561C-4023-A236-483BC458317DQ35645509-75A207F0-618A-42EE-8C2E-955AA34161D1Q36104883-7D3E4870-C9B4-4EC5-81BC-1D7F6A438553Q36109025-DF7DBF0F-A5F8-4531-B969-FA231D8E81E1Q36163897-FA9C1B04-C4B7-4E17-B3B2-BC42EC0A8CC5Q36300675-3C37475E-C189-4390-BB20-892412889EFEQ36603866-526E0259-BA79-450D-8E87-4E9BD9E46DCBQ36797684-005D6856-2F90-4303-824A-C78215CB82C5Q36938987-60E450CB-9EEC-4665-A0C7-0FE80F408A1BQ37014362-C696D820-E6A1-41EC-8B49-797EE1F0053CQ37201218-EE764A5F-1D72-4DDA-82FC-D6561278A257Q37475205-AE9C0B72-A025-4BCA-A054-79785E6FB50DQ37629047-984F480A-9AB2-4550-9004-CBA3B5099E3BQ37732104-54372E17-4200-4A0F-8350-5D65B4088C29Q38209734-9C7414DA-E7E0-4BAD-BEF2-ACE7F9B038B4Q38325539-D5B5EEDC-A66D-4157-90F0-7D642DACEB88Q38605684-9FBE0DD5-E3D1-493A-8567-729699C4D5D5Q38713135-62A3B460-5D79-4D1E-B9F8-8EE28476F08EQ38979959-DBA035CE-396F-4D07-B860-1E5834EFCB8AQ39038069-D7F698D0-C98D-48FB-A88F-C332E75B1E3BQ39069079-CC6634EF-5B7A-4404-88B0-B58DD1E105CCQ39241662-F89C3FCB-1C2C-48E1-9004-AF2B58BE02C8Q39726366-6DB7B3F6-B60B-4B56-BAB2-A1A389069A23Q49211331-522F6AC1-83C1-47D5-82C7-90688E90B032
P2860
A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A muscle-specific knockout imp ...... glucose and energy metabolism
@ast
A muscle-specific knockout imp ...... glucose and energy metabolism
@en
type
label
A muscle-specific knockout imp ...... glucose and energy metabolism
@ast
A muscle-specific knockout imp ...... glucose and energy metabolism
@en
prefLabel
A muscle-specific knockout imp ...... glucose and energy metabolism
@ast
A muscle-specific knockout imp ...... glucose and energy metabolism
@en
P2093
P2860
P356
P1476
A muscle-specific knockout imp ...... glucose and energy metabolism
@en
P2093
Kivanc Birsoy
Robert G Roeder
Xiaoting Zhang
P2860
P304
10196-10201
P356
10.1073/PNAS.1005626107
P407
P577
2010-05-17T00:00:00Z