Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes
about
Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?Cancer stem cell targeted therapy: progress amid controversies.Cell-associated transmission of HIV type 1 and other lentiviruses in small-animal modelsCan non-human primates serve as models for investigating dengue disease pathogenesis?New generation humanized mice for virus research: comparative aspects and future prospectsAnimal models for HIV/AIDS researchHIV-1 Env-specific memory and germinal center B cells in C57BL/6 miceCurrent humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis.Expansion of activated memory CD4+ T cells affects infectivity of CCR5-tropic HIV-1 in humanized NOD/SCID/JAK3null mice.The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment.Vectored antibody gene delivery for the prevention or treatment of HIV infection.What we are learning on HTLV-1 pathogenesis from animal models.In vivo platforms for analysis of HIV persistence and eradication.Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturationTopical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model.Mucosal HIV-1 transmission and prevention strategies in BLT humanized miceAnimal models for microbicide studies.A mouse model for human norovirus.Can humanized mice reflect the complex pathobiology of HIV-associated neurocognitive disorders?Human herpesvirus 6A infection and immunopathogenesis in humanized Rag2⁻/⁻ γc⁻/⁻ mice.HIV-1 immunopathogenesis in humanized mouse models.TALEN gene editing takes aim on HIV.HTLV-1 Infection and Neuropathogenesis in the Context of Rag1-/-γc-/- (RAG1-Hu) and BLT Mice.In Vivo Models of Human Immunodeficiency Virus Persistence and Cure Strategies.The Application of Humanized Mouse Models for the Study of Human Exclusive Viruses.Mucosal tissue pharmacokinetics of the integrase inhibitor raltegravir in a humanized mouse model: Implications for HIV pre-exposure prophylaxis.In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized micePDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice.Humanized Mice Engrafted With Human HSC Only or HSC and Thymus Support Comparable HIV-1 Replication, Immunopathology, and Responses to ART and Immune Therapy.
P2860
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P2860
Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Humanized Rag1-/- γc-/- mice s ...... ia systemic and vaginal routes
@ast
Humanized Rag1-/- γc-/- mice s ...... ia systemic and vaginal routes
@en
type
label
Humanized Rag1-/- γc-/- mice s ...... ia systemic and vaginal routes
@ast
Humanized Rag1-/- γc-/- mice s ...... ia systemic and vaginal routes
@en
prefLabel
Humanized Rag1-/- γc-/- mice s ...... ia systemic and vaginal routes
@ast
Humanized Rag1-/- γc-/- mice s ...... ia systemic and vaginal routes
@en
P2093
P2860
P1433
P1476
Humanized Rag1-/- γc-/- mice s ...... ia systemic and vaginal routes
@en
P2093
Bradford K Berges
Brent E Palmer
C Preston Neff
Elizabeth Connick
Jes Kuruvilla
Joy Folkvord
Kathy Gagliardi
Leila Remling
Ramesh Akkina
Sarah R Akkina
P2860
P304
P356
10.1371/JOURNAL.PONE.0020169
P407
P577
2011-06-14T00:00:00Z