Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses.
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Acute graft-versus-host disease: a bench-to-bedside update.Graft-versus-host disease in paediatric solid organ transplantation: A review of the literature.Conformal Nanoencapsulation of Allogeneic T Cells Mitigates Graft-versus-Host Disease and Retains Graft-versus-Leukemia Activity.Allogeneic bone marrow transplantation compared to peripheral blood stem cell transplantation for the treatment of hematologic malignancies: a meta-analysis based on time-to-event data from randomized controlled trials.Advances in graft-versus-host disease biology and therapy.Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levelsCD4+ T cell STAT3 phosphorylation precedes acute GVHD, and subsequent Th17 tissue invasion correlates with GVHD severity and therapeutic response.Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen.Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantationThe IL-33/ST2 axis augments effector T-cell responses during acute GVHD.Essential Role of Interleukin-12/23p40 in the Development of Graft-versus-Host Disease in Mice.Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation.Essentials of Th17 cell commitment and plasticityA critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease.Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease.Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.Regulatory T cells and IL-17-producing cells in graft-versus-host disease.The IL-17 differentiation pathway and its role in transplant outcome.New ways to separate graft-versus-host disease and graft-versus-tumour effects after allogeneic haematopoietic stem cell transplantation.Helper T-cell differentiation in graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.Translational opportunities for targeting the Th17 axis in acute graft-vs.-host disease.Altered homeostatic regulation of innate and adaptive immunity in lower gastrointestinal tract GVHD pathogenesis.Selective expansion of human natural killer cells leads to enhanced alloreactivityBlockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression.
P2860
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P2860
Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Blockade of interleukin-23 sig ...... aft-versus-leukemia responses.
@ast
Blockade of interleukin-23 sig ...... aft-versus-leukemia responses.
@en
type
label
Blockade of interleukin-23 sig ...... aft-versus-leukemia responses.
@ast
Blockade of interleukin-23 sig ...... aft-versus-leukemia responses.
@en
prefLabel
Blockade of interleukin-23 sig ...... aft-versus-leukemia responses.
@ast
Blockade of interleukin-23 sig ...... aft-versus-leukemia responses.
@en
P2093
P2860
P1433
P1476
Blockade of interleukin-23 sig ...... aft-versus-leukemia responses.
@en
P2093
Claudia S Huettner
Daniel Cua
Hariharan Subramanian
Martin J Hessner
Richard Komorowski
Rupali Das
William R Drobyski
P2860
P304
P356
10.1182/BLOOD-2009-11-255422
P407
P577
2010-04-09T00:00:00Z