Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. - sprookjes - yvandenbroek - TriplyDB

Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

http://www.wikidata.org/entity/Q33947166

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Stable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding deoxynucleoside triphosphates or foscarnet Human replication protein A can suppress the intrinsic in vitro mutator phenotype of human DNA polymerase lambda.A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson-Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.Role of the catalytic metal during polymerization by DNA polymerase lambda A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation Versatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine Adducts Early Interrogation and Recognition of DNA Sequence by Indirect Readout Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase ι Impact of Conformational Heterogeneity of OxoG Lesions and Their Pairing Partners on Bypass Fidelity by Y Family Polymerases Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXES Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4 Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4 Structural basis for the suppression of skin cancers by DNA polymerase η Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 fromSulfolobus solfataricus Replication infidelity via a mismatch with Watson–Crick geometry The Y-Family DNA Polymerase Dpo4 Uses a Template Slippage Mechanism To Create Single-Base Deletions The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase Implications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C Lesions Differential Furanose Selection in the Active Sites of Archaeal DNA Polymerases Probed by Fixed-Conformation Nucleotide Analogues Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis Y-Family Polymerase Conformation Is a Major Determinant of Fidelity and Translesion Specificity Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η.Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.Structural Mechanism of Replication Stalling on a Bulky Amino-Polycyclic Aromatic Hydrocarbon DNA Adduct by a Y Family DNA Polymerase Metal-Dependent Conformational Activation Explains Highly Promutagenic Replication across O6-Methylguanine by Human DNA Polymerase β Unlocking the sugar "steric gate" of DNA polymerases An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η Cofactor requirement of HpyAV restriction endonuclease The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies.Global conformational dynamics of a Y-family DNA polymerase during catalysis.Effect of A and B metal ion site occupancy on conformational changes in an RB69 DNA polymerase ternary complex.Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta.

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P2860

Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

http://www.wikidata.org/entity/Q33947166

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2005 nî lūn-bûn

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

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SJ.EMBOJ.7600786

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The EMBO Journal

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.

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Hong Ling

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Roger Woodgate

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Wei Yang

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P2860

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA

Structure of the replicating complex of a pol alpha family DNA polymerase

Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain

Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication

Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus

Replication of a cis-syn thymine dimer at atomic resolution

Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

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Alexandra Vaisman

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