A synthetic antimicrobial peptidomimetic (LTX 109): stereochemical impact on membrane disruption.
about
Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albuminAryl-Alkyl-Lysines: Agents That Kill Planktonic Cells, Persister Cells, Biofilms of MRSA and Protect Mice from Skin-InfectionAntibiotics in the clinical pipeline at the end of 2015.The synthetic amphipathic peptidomimetic LTX109 is a potent fungicide that disturbs plasma membrane integrity in a sphingolipid dependent mannerLTX-109 is a novel agent for nasal decolonization of methicillin-resistant and -sensitive Staphylococcus aureus.Antifungal properties of peptidomimetics with an arginine-[β-(2,5,7-tri-tert-butylindol-3-yl)alanine]-arginine motif against Saccharomyces cerevisiae and Zygosaccharomyces bailii.Evaluation of cationic micropeptides derived from the innate immune system as inhibitors of marine biofouling.Membrane-Active Small Molecules: Designs Inspired by Antimicrobial Peptides.In vitro activities of LTX-109, a synthetic antimicrobial peptide, against methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, daptomycin-nonsusceptible, and linezolid-nonsusceptible Staphylococcus aureusThe Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for Polymicrobial Infected WoundsMembrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design.Small Antimicrobial Agents Based on Acylated Reduced Amide Scaffold.The chemistry and biology of organic guanidine derivatives.Peptides as the next generation of anti-infectives.Combating multidrug-resistant Gram-negative bacterial infections.Natural product and natural product derived drugs in clinical trials.Antimicrobial benzodiazepine-based short cationic peptidomimetics.l-Lysine based lipidated biphenyls as agents with anti-biofilm and anti-inflammatory properties that also inhibit intracellular bacteria.Short Synthetic β-Sheet Antimicrobial Peptides for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Burn Wound Infections.Designing Simple Lipidated Lysines: Bifurcation Imparts Selective Antibacterial Activity.Antimicrobial peptides and their analogs: searching for new potential therapeutics.Short cationic antimicrobial peptides bind to human alpha-1 acid glycoprotein with no implications for the in vitro bioactivity.Amphipathic guanidine-embedded glyoxamide-based peptidomimetics as novel antibacterial agents and biofilm disruptors.Synthesis and biological evaluation of N-naphthoyl-phenylglyoxamide-based small molecular antimicrobial peptide mimics as novel antimicrobial agents and biofilm inhibitors.Antibacterial Diamines Targeting Bacterial Membranes.
P2860
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P2860
A synthetic antimicrobial peptidomimetic (LTX 109): stereochemical impact on membrane disruption.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A synthetic antimicrobial pept ...... impact on membrane disruption.
@ast
A synthetic antimicrobial pept ...... impact on membrane disruption.
@en
type
label
A synthetic antimicrobial pept ...... impact on membrane disruption.
@ast
A synthetic antimicrobial pept ...... impact on membrane disruption.
@en
prefLabel
A synthetic antimicrobial pept ...... impact on membrane disruption.
@ast
A synthetic antimicrobial pept ...... impact on membrane disruption.
@en
P2093
P356
P1476
A synthetic antimicrobial pept ...... impact on membrane disruption.
@en
P2093
Bjørn O Brandsdal
Gøril Eide Flaten
Johan Isaksson
John S Mjøen Svendsen
Magnus Engqvist
Wenche Stensen
P304
P356
10.1021/JM200450H
P407
P577
2011-07-26T00:00:00Z