TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling.
about
NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic ImplicationsControl of autoimmune CNS inflammation by astrocytesIntestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis.Tumor progression locus 2 differentially regulates IFNγ and IL-17 production by effector CD4+ T cells in a T cell transfer model of colitisTumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells.The role of IL-17 in CNS diseases.Tpl2 promotes innate cell recruitment and effector T cell differentiation to limit Citrobacter rodentium burden and dissemination.TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury.Post-Translational Modifications of the TAK1-TAB Complex.IL-17 Signaling: The Yin and the Yang.IL-17-triggered downregulation of miR-497 results in high HIF-1α expression and consequent IL-1β and IL-6 production by astrocytes in EAE mice.Tpl2 promotes neutrophil trafficking, oxidative burst, and bacterial killing.Anti-inflammatory activity of AP-SF, a ginsenoside-enriched fraction, from Korean ginsengThe Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold.A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion.TPL2 mediates IL-17R signaling in neuroinflammation.Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate.RKIP mediates autoimmune inflammation by positively regulating IL-17R signaling.Protein Kinase Serine/Threonine Kinase 24 Positively Regulates Interleukin 17-Induced Inflammation by Promoting IKK Complex Activation.A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation
P2860
Q28078299-990E690B-5515-470A-A62D-CFC7EAE50AFEQ28084132-EE114E17-E311-4B9E-8F86-F485E118BE5CQ34441916-904DC33B-F65D-4C59-BE79-CF7C9A60CFAEQ35187958-304828C2-1463-46AB-8BA3-160D3A69A9AEQ37626144-D728F770-A3CC-4401-A973-F60CCEA64749Q38365272-80959EAE-9C2D-458A-80FC-5E5236377770Q38650821-EC0844D3-128C-4F79-860D-8C09A83A8391Q38780085-5011CBB3-E9A4-475B-8E9B-9EAF9DB3E394Q39096576-4B9B6DF8-8B3A-4548-8466-542BEBE036D5Q39158530-0A85AD3A-02E5-4D90-B344-B5575E450233Q40231889-D5E41364-93CF-4BA2-814F-1933767378C5Q40273190-8A54FC53-5B2B-48B9-B67C-923EBF9D62DEQ41577043-CD7FD4B1-EC30-402A-BCB5-E677C7C82EF2Q41825901-2FBFD72E-6072-4475-9D51-3FEB171CD922Q42741761-677F2093-5BF8-4F61-B41D-773E0D532B23Q43139032-49489D45-EFFD-4749-A69A-9FE67B89E25EQ49920636-E735C42F-7936-491F-AD4C-4C3E7286DC22Q52315081-2A29732F-83E5-483A-AE00-2F6D426C7673Q54109918-91868B4E-C2F0-420D-BB6D-15934DE942D4Q58610859-56A9AEC4-2E26-4E63-9C9B-7A81C5EB5A1E
P2860
TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
TPL2 mediates autoimmune infla ...... TAK1 axis of IL-17 signaling.
@ast
TPL2 mediates autoimmune infla ...... TAK1 axis of IL-17 signaling.
@en
type
label
TPL2 mediates autoimmune infla ...... TAK1 axis of IL-17 signaling.
@ast
TPL2 mediates autoimmune infla ...... TAK1 axis of IL-17 signaling.
@en
prefLabel
TPL2 mediates autoimmune infla ...... TAK1 axis of IL-17 signaling.
@ast
TPL2 mediates autoimmune infla ...... TAK1 axis of IL-17 signaling.
@en
P2093
P2860
P356
P1476
TPL2 mediates autoimmune infla ...... e TAK1 axis of IL-17 signaling
@en
P2093
George C Brittain
Mako Nakaya
Mikyoung Chang
Shao-Cong Sun
Xiaofei Zhou
Xuhong Cheng
Yichuan Xiao
P2860
P304
P356
10.1084/JEM.20132640
P407
P50
P577
2014-06-30T00:00:00Z