Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.
about
GPR109A and vascular inflammationTransactivation of epidermal growth factor receptor through platelet-activating factor/receptor in ovarian cancer cells.Niacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.Distinct pathways of ERK1/2 activation by hydroxy-carboxylic acid receptor-1Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors.Activated human hydroxy-carboxylic acid receptor-3 signals to MAP kinase cascades via the PLC-dependent PKC and MMP-mediated EGFR pathways.Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization.Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.Long-term niacin treatment induces insulin resistance and adrenergic responsiveness in adipocytes by adaptive downregulation of phosphodiesterase 3B.Purinergic signaling, dyslipidemia and inflammatory disease.Distinct kinetic and spatial patterns of protein kinase C (PKC)- and epidermal growth factor receptor (EGFR)-dependent activation of extracellular signal-regulated kinases 1 and 2 by human nicotinic acid receptor GPR109A.The nutrition-gut microbiome-physiology axis and allergic diseases.Valproic Acid Influences MTNR1A Intracellular Trafficking and Signaling in a β-Arrestin 2-Dependent Manner.Butyrate attenuates lipolysis in adipocytes co-cultured with macrophages through non-prostaglandin E2-mediated and prostaglandin E2-mediated pathways.BNGR-A25L and -A27 are two functional G protein-coupled receptors for CAPA periviscerokinin neuropeptides in the silkworm Bombyx mori.Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptor.Porcine sapovirus Cowden strain enters LLC-PK cells via clathrin- and cholesterol-dependent endocytosis with the requirement of dynamin II
P2860
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P2860
Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Internalization of the human n ...... by G(i), GRK2, and arrestin3.
@ast
Internalization of the human n ...... by G(i), GRK2, and arrestin3.
@en
type
label
Internalization of the human n ...... by G(i), GRK2, and arrestin3.
@ast
Internalization of the human n ...... by G(i), GRK2, and arrestin3.
@en
prefLabel
Internalization of the human n ...... by G(i), GRK2, and arrestin3.
@ast
Internalization of the human n ...... by G(i), GRK2, and arrestin3.
@en
P2093
P2860
P356
P1476
Internalization of the human n ...... by G(i), GRK2, and arrestin3.
@en
P2093
Haishan Huang
Jeffrey L Benovic
Jiansong Luo
Jianxin Lu
Kuangpei Wu
Naiming Zhou
Yaping Zhang
P2860
P304
22605-22618
P356
10.1074/JBC.M109.087213
P407
P577
2010-05-11T00:00:00Z