Structure of the biologically relevant G-quadruplex in the c-MYC promoter. - sprookjes - yvandenbroek - TriplyDB

Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation I-motif structures formed in the human c-MYC promoter are highly dynamic--insights into sequence redundancy and I-motif stability Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin "One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.The formation and stabilization of a novel G-quadruplex in the 5'-flanking region of the relaxin gene.Thermodynamic stability and folding kinetics of the major G-quadruplex and its loop isomers formed in the nuclease hypersensitive element in the human c-Myc promoter: effect of loops and flanking segments on the stability of parallel-stranded intram The C-terminus of nucleolin promotes the formation of the c-MYC G-quadruplex and inhibits c-MYC promoter activity.The polyoma virus large T binding protein p150 is a transcriptional repressor of c-MYC The role of G-quadruplex/i-motif secondary structures as cis-acting regulatory elements.Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4 Ion-dependent conformational switching by a DNA aptamer that induces remyelination in a mouse model of multiple sclerosis.Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.G-register exchange dynamics in guanine quadruplexes.First International Meeting on Quadruplex DNA.Stability and kinetics of G-quadruplex structures Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions.Polymorphism of human telomeric quadruplex structures AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein Genome-wide colonization of gene regulatory elements by G4 DNA motifs The i-motif in the bcl-2 P1 promoter forms an unexpectedly stable structure with a unique 8:5:7 loop folding pattern.Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences.G-quadruplexes as potential therapeutic targets for embryonal tumors.A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity.Discrimination of G-quadruplexes from duplex and single-stranded DNAs with fluorescence and energy-transfer fluorescence spectra of crystal violet.The MYCN Protein in Health and Disease.Genomic c-Myc quadruplex DNA selectively kills leukemia.Bifunctional Zn(II) complexes for recognition of non-canonical thymines in DNA bulges and G-quadruplexes.Small molecule selectively suppresses MYC transcription in cancer cells.SMARCAL1 Negatively Regulates C-Myc Transcription By Altering The Conformation Of The Promoter Region.Allelic Dropout During Polymerase Chain Reaction due to G-Quadruplex Structures and DNA Methylation Is Widespread at Imprinted Human Loci.A genome-inspired, reverse selection approach to aptamer discovery.Ethyl-substitutive Thioflavin T as a highly-specific fluorescence probe for detecting G-quadruplex structure.Transformation of a Thermostable G-Quadruplex Structure into DNA Duplex Driven by Reverse Gyrase.Bioanalytical Application of Peroxidase-Mimicking DNAzymes: Status and Challenges.Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations.A G-Quadruplex Structure in the Promoter Region of Functions as a Regulatory Element for Gene Expression

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P2860

Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Nucleosides, Nucleotides & Nucleic Acids

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Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

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Danzhou Yang

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Laurence H Hurley

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P2860

MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

Transcriptional consequences of topoisomerase inhibition

A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations

An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction

Intramolecular higher order packing of parallel quadruplexes comprising a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad of GGA triplet repeat DNA

Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

DNA tetraplex formation in the control region of c-myc

The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma

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